Actively Recruiting
A Study on Yiyang Huoluo Decoction in the Treatment of Coronary Heart Disease
Led by Xia Liang · Updated on 2026-03-25
30
Participants Needed
1
Research Sites
128 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to learn if Yiyang Huoluo Decoction (a custom Chinese herbal medicine) works safely and effectively to treat coronary heart disease with atherosclerosis in older adults. It also aims to find out how this herbal treatment may affect blood vessel health and repair at a cellular level. The main questions it aims to answer are: * Does adding Yiyang Huoluo Decoction to standard Western medical care improve symptoms and heart-related health in older adults with coronary heart disease and atherosclerosis? * Is Yiyang Huoluo Decoction safe for older adults to take alongside their regular heart medications? * How does this herbal treatment affect the damaged blood vessels in study participants? Researchers will compare two groups of participants to see if the combined treatment works better than standard care alone. Who can take part: Older adults diagnosed with coronary heart disease and atherosclerosis who meet the study's health and eligibility rules. What participants will do: * Be split randomly into two groups of 15 people each: one group gets standard Western heart medicine only, and the other gets standard Western heart medicine plus Yiyang Huoluo Decoction (herbal granules) * Complete the 12-week decoction treatment plan as directed by the research team * Attend scheduled study visits for health checks, blood tests, heart and blood vessel scans (such as carotid ultrasound and coronary CTA), and symptom reviews * Provide two small blood samples for research testing (samples will be destroyed after study testing is finished) * Report any side effects, discomfort, or changes in health to the research team right away All personal health information collected for this study will be kept private and confidential. Participation is completely voluntary, and participants may quit the study at any time for any reason without losing access to regular medical care.
CONDITIONS
Official Title
A Study on Yiyang Huoluo Decoction in the Treatment of Coronary Heart Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Meet the diagnostic criteria for stable angina pectoris
- Classified as Grade I to III according to the Canadian Cardiovascular Society Angina Grading Scale
- Meet the diagnostic criteria for chest discomfort syndrome due to yang qi deficiency and decline
- Aged between 50 and 75 years old
- Received drug-eluting stent implantation for severe vascular stenosis (single artery 65%, or left main 60%) confirmed by coronary angiography
- Able to follow medical instructions and voluntarily sign informed consent
You will not qualify if you...
- Diagnosed with acute coronary syndrome, including acute ST-segment elevation myocardial infarction, acute non-ST-segment elevation myocardial infarction, or unstable angina pectoris
- Chest pain caused by non-cardiac diseases or complicated severe hypertension (systolic 65 180mmHg and/or diastolic 65 110mmHg), severe cardiopulmonary insufficiency, or malignant tumor
- Severe endocrine, blood, rheumatic immune diseases, severe liver or kidney dysfunction, active gastrointestinal bleeding, or mental illness
- Allergic constitution or history of allergic reactions to traditional Chinese medicine
- Incomplete major baseline data affecting trial results or recent participation in other clinical trials
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
People's Hospital of Anji
Huzhou, Zhejiang, China
Actively Recruiting
Research Team
L
Liang Xia, Doctor
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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