Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
ID06961838

The Effect of Inspiratory Muscle Training With Substance Use Disorder

Led by Uskudar University · Updated on 2026-05-05

34

Participants Needed

1

Research Sites

4 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to evaluate the effects of inspiratory muscle training on individuals with substance use disorder (SUD). It investigates how this training influences breathing difficulty (dyspnea), lung function, respiratory muscle strength, cough capacity, exercise ability, substance craving, depression, anxiety, and overall quality of life. The study addresses the rising substance use among young people and explores a potentially simple and cost-effective treatment method to support respiratory health in this group. Participants are divided into two groups: one group receives standard treatment plus inspiratory muscle training using a device called POWERbreathe®, performing 15-minute sessions twice daily for five days a week over four weeks under physiotherapist supervision. The other group continues with their standard treatment alone without additional exercises. The inspiratory muscle training aims to improve respiratory function and reduce symptoms related to substance use. During the study, participants will undergo assessments at four weeks measuring breathing difficulty, various lung function parameters (such as FEV1, FVC, and others), respiratory muscle strength, cough capacity, and exercise capacity. Additional evaluations include substance craving levels, mental health symptoms like anxiety and depression, and quality of life. The study follows participants throughout the treatment period to monitor changes and gather data on the effectiveness of the inspiratory muscle training.

CONDITIONS

Brief Title

The Effect of Inspiratory Muscle Training With Substance Use Disorder

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Being 18 years or older
  • Meeting DSM-5 criteria for Substance Use Disorder
  • Receiving inpatient treatment
  • Substance use for more than one year
  • Able to follow simple instructions
  • No visual or auditory impairments
  • Able to cooperate with study devices
Not Eligible

You will not qualify if you...

  • Not following the treatment and assessment program
  • Participated in structured physiotherapy or exercise in last 6 months
  • Current psychotic symptoms
  • Any physical disability or medical problem
  • Respiratory problems such as asthma or tuberculosis
  • Infectious diseases like HIV or hepatitis B

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - 4 weeks

Participants in the inspiratory muscle training group will perform inspiratory muscle training for 15 minutes twice a day, 5 days a week for 4 weeks under physiotherapist supervision alongside their standard treatment. Participants in the control group will continue their standard treatment without additional intervention.

Supervised training sessions 5 days per week for 4 weeks

Trial Site Locations

Total: 1 location

1

Üsküdar University

Istanbul, Turkey, Turkey (Türkiye)

Actively Recruiting

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Research Team

B

Beyzanur D Research Assistant

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Published Research Related To This Trial

Effect of manually assisted cough and mechanical insufflation on cough flow of normal subjects, patients with chronic obstructive pulmonary disease (COPD), and patients with respiratory muscle weakness.

P Sivasothy, L Brown, I E Smith...

https://pubmed.ncbi.nlm.nih.gov/11359958