An Investigation of Different Type Single Limb Exercise Training Effects on Functional Capacity, Arterial Stiffness, Muscle Activation and Quality of Life in Chronic Obstructive Pulmonary Disease

What this Trial Is About

Researchers are evaluating the effects of three different types of single-leg exercise training on people with Chronic Obstructive Pulmonary Disease (COPD). COPD affects not only breathing but also blood vessel and muscle function, leading to exercise limitations and muscle fatigue. This trial focuses on how these exercise methods influence exercise capacity, muscle strength, lung function, muscle activity, lactate levels, arterial stiffness, and quality of life in COPD patients. The study divides participants into three groups, each receiving a different single-leg exercise training for six weeks: continuous exercise, high-intensity interval training, or resistance training. Each group performs their assigned exercise to assess changes in physical and respiratory function. Measurements include muscle strength tests, lung function evaluations, electromyography recordings, and lactate and arterial stiffness assessments. Participants will undergo tests before and after the intervention period, including a six-minute walk test, cardiopulmonary exercise tests, muscle strength assessments, and quality of life questionnaires. These evaluations help researchers monitor changes in functional capacity and health status. The study is randomized with single masking to compare the effects of the different exercise types over the six-week training period.

An Investigation of Different Type Single Limb Exercise Training Effects in Copd