Actively Recruiting
Effect of Inulin on Gut Microbiota and Gut Barrier in Chronic Kidney Disease
Led by Charite University, Berlin, Germany · Updated on 2024-06-25
40
Participants Needed
1
Research Sites
260 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
An adequate fiber intake is crucial for a well-balanced diet and reduces the risk of chronic diseases. However, nutritional recommendations for chronic kidney disease patients lead to an insufficient fiber intake with possible maladaptive effects on the gut microbiome. Therefore, we want to study the effects of a 35-day inulin supplementation on the gut microbiome, gut barrier function, bacterial metabolites and immune cell states in chronic kidney disease patients.
CONDITIONS
Official Title
Effect of Inulin on Gut Microbiota and Gut Barrier in Chronic Kidney Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Men and women in a ratio of 1:1
- Age between 18 and 75 years
- Body mass index between 18.5 and 39.9 kg/m²
- End-stage kidney disease treated regularly with hemodialysis for at least 3 months
You will not qualify if you...
- Malignant diseases
- Recent or current hospitalization
- Postoperative phase
- Acute infections
- Malnutrition
- Antibiotic treatment within the last 4 weeks
- Regular intake of probiotics and/or prebiotics
- Change of body weight of more than 2 kg in the month prior to study entry
- Known drug or alcohol abuse
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Experimental and Clinical Research Center
Berlin, Germany, 13125
Actively Recruiting
Research Team
V
Victoria McParland, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here