Actively Recruiting
An Investigation of the Effectiveness of the BETY Exercise Program Based on the Biopsychosocial Model in Individuals With Knee Osteoarthritis Who Have Received Intra-articular Injections
Led by Hacettepe University · Updated on 2026-03-27
60
Participants Needed
1
Research Sites
88 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Osteoarthritis (OA) of the knee is a common condition in middle-aged and older adults that causes pain, disability, and inflammation. This research evaluates the BETY exercise program, which is based on the biopsychosocial model and includes body stabilization, pain management, mood and emotion therapy, and sexuality information. The study aims to investigate how BETY may help people with knee OA who have recently received intra-articular injections, a treatment used to reduce inflammation and support cartilage repair. Participants will be randomly assigned to one of three groups: the BETY exercise group, a traditional exercise group, or a control group. The traditional exercise group will perform active range-of-motion and muscle strengthening exercises for the knee and lower extremity. The study starts in early 2026 and includes a single-blind design to monitor effects over time. During the study, participants will be assessed at regular intervals up to six months. Researchers will measure outcomes such as muscle strength, the BETY-BQ questionnaire, and various health and function tests including pain, anxiety, depression, walking ability, and muscle endurance. These evaluations will help determine the program's impact on physical function and quality of life for individuals with knee OA who have had intra-articular injections.
CONDITIONS
Brief Title
The Effectiveness of BETY in Knee Osteoarthritis With Intra-Articular Injections
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of knee osteoarthritis according to ACR knee osteoarthritis diagnostic criteria
- Stage 2 or 3 according to Kellgren-Lawrence radiological staging criteria
- Received an intra-articular injection in the knee within the past month
- 18 years of age or older
- Able to read and write
- Signed informed consent
You will not qualify if you...
- History of major psychiatric illness
- Having malignant disease
- Having chronic infectious or other rheumatologic diseases
- Serious knee trauma or surgical operation in the last 6 months
- Having collagen tissue disease
- History of peripheral vascular disease or neuropathy
- Stage 4 according to Kellgren-Lawrence radiologic staging criteria
- Received a physiotherapy program for the relevant knee in the last 3 months
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - 6 months
Participants follow one of the exercise programs, including active range-of-motion, muscle strengthening, and stretching exercises targeting the knee and lower extremity muscle groups.
Trial Site Locations
Total: 1 location
1
Hacettepe University
Ankara, Samanpazarı, Turkey (Türkiye), 06100
Actively Recruiting
Research Team
A
Aysima Barlak, PT, MSc
E
Edibe Ünal, PT, Prof
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
3
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