Actively Recruiting

Phase Not Applicable
Age: 40Years +
All Genders
ID06971016

Effectiveness of Mulligan Mobilization Technique and Proprioceptive Exercises Among Patients With Knee Osteoarthritis in Karachi

Led by National Healthcare Center · Updated on 2025-05-21

60

Participants Needed

1

Research Sites

8 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating the effectiveness of Mulligan Mobilization Technique compared to proprioceptive exercises for treating adults aged 40 and above with mild to moderate knee osteoarthritis, classified as Grades 2 and 3 on the Kellgren and Lawrence scale. The study aims to assess these treatments over a 10-week period, focusing on pain levels, movement, functional activities, balance, and quality of life improvements. Participants are selected based on clinical diagnosis and mobility ability without assistive devices. The study involves three groups: one receiving proprioceptive exercises designed to improve balance and joint position sense, another receiving Mulligan Mobilization Technique, a manual therapy to improve joint mobility, and a control group undergoing traditional physical therapy. Each participant receives 30 treatment sessions over 10 weeks, with three sessions per week lasting 40 to 60 minutes each. Treatments are delivered by trained physical therapists, and assessments occur at the start and end of the treatment period. Participants will complete questionnaires and undergo evaluations measuring pain intensity, range of motion, functional status, and balance using tools like the Numeric Pain Rating Scale, Universal Goniometer, Knee Injury and Osteoarthritis Outcome Score, and Berg Balance Scale. Quality of life is also assessed using the SF-36 questionnaire. The study follows a double-blind, randomized design to ensure unbiased results. Confidentiality is maintained, and participants may withdraw at any time without penalty.

CONDITIONS

Brief Title

"Effectiveness of Mulligan Mobilization Technique and Proprioceptive Exercises Among Patients With Knee Osteoarthritis"

Who Can Participate

Age: 40Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed cases of knee osteoarthritis with mild to moderate grade (Grades 2 or 3) according to the Kellgren and Lawrence scale
  • Ability to walk without assistive devices for at least 50 feet
  • Age 40 years or older
Not Eligible

You will not qualify if you...

  • Knee osteoarthritis with grade less than 2 or greater than 3 on the Kellgren and Lawrence scale
  • History of knee surgery or knee joint replacement
  • Corticosteroid injections administered in the last six months
  • History of mental illness, autoimmune disorders, neurological or orthopedic conditions affecting lower limbs
  • Presence of any other conditions affecting balance or gait

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - 10 weeks

Participants receive one of three treatment interventions: Mulligan Mobilization Technique, Proprioceptive Exercises, or Traditional Physical Therapy to improve knee osteoarthritis symptoms including pain, range of motion, balance, and function.

30 sessions, each lasting approximately 45 minutes

Trial Site Locations

Total: 1 location

1

National Healthcare Center

Karachi, Sindh, Pakistan, 75600

Actively Recruiting

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Research Team

M

Muhammad Atif Khan, PhD Scholar

A

Atif Hussain Hussain

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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Published Research Related To This Trial

Immediate effects of Maitland mobilization versus Mulligan Mobilization with Movement in Osteoarthritis knee- A Randomized Crossover trial.

Ramya V Rao, Ganesh Balthillaya, Anupama Prabhu...

https://pubmed.ncbi.nlm.nih.gov/30100279