Exercise- and education-based prehabilitation before total knee arthroplasty: a pilot study.
Pascale Gränicher, Loes Mulder, Ton Lenssen...
https://pubmed.ncbi.nlm.nih.gov/38192160Actively Recruiting
Phase Not Applicable
Age: 45Years - 80Years
All Genders
ID06721897
Effectiveness of a Prehabilitation Program on Clinical, Functional and Psychological Variables in Candidates for Hip or Knee Arthroplasty Surgery
Led by University of Jaén · Updated on 2026-02-13
44
Participants Needed
1
Research Sites
8 weeks
Total Duration
On this page
Sponsors
U
University of Jaén
Lead Sponsor
H
Hospital Clinico Universitario San Cecilio
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are studying the effects of a prehabilitation program on patients with hip or knee osteoarthritis who are awaiting arthroplasty surgery. Osteoarthritis is a joint disease causing pain, stiffness, and reduced function, often affecting the hip and knee. This study aims to find out whether prehabilitation can improve recovery times, functional ability, and psychological wellbeing after surgery, offering a non-drug, non-invasive treatment option. Participants in the intervention group will follow a 6-week supervised prehabilitation program before surgery, including strength, balance, cardiovascular, and flexibility exercises. After surgery, they will receive the same rehabilitation program as the control group. The control group will begin a post-operative physiotherapy and home exercise program after hospital discharge. The study compares these approaches to see how prehabilitation affects outcomes. During the study, participants will be assessed on quality of life, lower limb function, strength, pain, psychological factors, sleep quality, and medication use at various points from before prehabilitation through 24 weeks after surgery. Researchers will monitor adherence to therapy and measure body composition and biochemical markers. The goal is to understand how prehabilitation influences recovery and overall health in patients undergoing hip or knee replacement.
CONDITIONS
Brief Title
Effectiveness of a Prehabilitation Program for Hip or Knee Arthroplasty Surgery.
Who Can Participate
Age: 45Years - 80Years
All Genders
Eligibility Criteria
You may qualify if you...
- Diagnosis of hip osteoarthritis stage I-III or knee osteoarthritis stage I-IV
- Patients requiring hip or knee arthroplasty surgery
- Signed informed consent
- Able to complete at least 8 repetitions in the Sit to Stand test
- Able to walk without technical aids or with limited help (up to two canes or a walker)
You will not qualify if you...
- Cognitive deficits or dementia
- Cancer
- Vascular or inflammatory diseases
- Neurological disorders
- Contraindications to physical exercise
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Prehabilitation Program
Duration - 6 weeks
Participants in the intervention group undergo a 6-week prehabilitation program supervised by a physiotherapist, including 3 sessions per week lasting 30 to 45 minutes each, plus daily home exercises focusing on flexibility and proprioception.
3 supervised sessions per week and daily home exercises
Surgery and Immediate Post-operative Care
Duration - 1 to 2 days post-surgery
Participants undergo hip or knee arthroplasty surgery followed by immediate post-operative care.
1 hospital stay for surgery and immediate recovery
Post-operative Rehabilitation
Duration - Up to 18 weeks following surgery
Participants in both groups follow a post-operative physiotherapy program along with a home exercise program demonstrated before hospital discharge.
Multiple physiotherapy sessions and home exercises as prescribed
Follow-up Assessments
Duration - Up to 24 weeks from study start
Participants complete follow-up assessments evaluating quality of life, functionality, strength, pain, psychological aspects, sleep quality, analgesic use, therapeutic adherence, and other clinical parameters up to 24 weeks after starting the study.
Visits at week 6, week 9, and week 24 for assessments
Trial Site Locations
Total: 1 location
1
Hospital Universitario San Cecilio- Distrito Sanitario Metropolitano Granada
Granada, Spain, 18012
Actively Recruiting
Loading map...
Research Team
I
IRENE MARIA IMLP LOPERA, Investigator
I
IRENE IMAGINO LOPERA, Principal Investigator
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here
Published Research Related To This Trial
Impact of a Six-Week Prehabilitation With Blood-Flow Restriction Training on Pre- and Postoperative Skeletal Muscle Mass and Strength in Patients Receiving Primary Total Knee Arthroplasty.
Alexander Franz, Sanghyeon Ji, Bernd Bittersohl...
https://pubmed.ncbi.nlm.nih.gov/35774280Prehabilitation before total knee arthroplasty increases strength and function in older adults with severe osteoarthritis.
Ann M Swank, Joseph B Kachelman, Wendy Bibeau...
https://pubmed.ncbi.nlm.nih.gov/21217530The effect of a prehabilitation exercise program on quadriceps strength for patients undergoing total knee arthroplasty: a randomized controlled pilot study.
Carly McKay, Harry Prapavessis, Timothy Doherty
https://pubmed.ncbi.nlm.nih.gov/22698852Global management of patients with knee osteoarthritis begins with quality of life assessment: a systematic review.
Marianna Vitaloni, Angie Botto-van Bemden, Rosa Maya Sciortino Contreras...
https://pubmed.ncbi.nlm.nih.gov/31656197Effect of Prehabilitation Before Total Knee Replacement for Knee Osteoarthritis on Functional Outcomes: A Randomized Clinical Trial.
Christelle Nguyen, Isabelle Boutron, Alexandra Roren...
https://pubmed.ncbi.nlm.nih.gov/35262716Evidence on risk factors for knee osteoarthritis in middle-older aged: a systematic review and meta analysis.
Yawei Dong, Yan Yan, Jun Zhou...
https://pubmed.ncbi.nlm.nih.gov/37641050The Effect of Prehabilitation on Postoperative Outcome in Patients Following Primary Total Knee Arthroplasty.
Dzenan Jahic, Djemil Omerovic, Adnana Talic Tanovic...
https://pubmed.ncbi.nlm.nih.gov/30814777Home-based pre-surgical psychological intervention for knee osteoarthritis (HAPPiKNEES): a feasibility randomized controlled trial.
Roshan das Nair, Jacqueline R Mhizha-Murira, Pippa Anderson...
https://pubmed.ncbi.nlm.nih.gov/29424236Effect of Systematic Exercise Rehabilitation on Patients With Knee Osteoarthritis: A Randomized Controlled Trial.
Jing Chao, Zhang Jing, Bai Xuehua...
https://pubmed.ncbi.nlm.nih.gov/32037857