Effects of Omega-3 Fish Oil Supplements Combined With Twice-Weekly Resistance Training on Muscle Health in Adults With Various Cancers

What this Trial Is About

Cancer cachexia is a serious complication that occurs in advanced cancer patients, causing muscle loss, reduced physical performance, and lower quality of life. It results from inflammation, increased breakdown of body tissue, and poor nutrition. This trial studies whether combining resistance training and omega-3 fatty acid supplements can improve muscle health and patient well-being in adults with various cancers, including gynecological, gastrointestinal, and urological types. Participants are randomly assigned to one of four groups placebo capsules with no exercise, placebo with twice-weekly resistance training, omega-3 fish oil capsules with no exercise, or omega-3 fish oil capsules combined with twice-weekly resistance training. The omega-3 supplement includes daily intake of 2 grams EPA and 1 gram DHA through fish oil capsules. The training involves progressive resistance exercises using TheraBand twice per week, with the study lasting 12 weeks. Throughout the study, participants undergo assessments at baseline, 3, 6, 9, and 12 weeks, with follow-up evaluations six months after completion. Measures include skeletal muscle status, physical performance, nutritional status, and patient-reported outcomes such as quality of life and fatigue. The study monitors safety and adherence to the interventions, aiming to understand how these combined methods affect muscle health and related symptoms in cancer patients.

Effects of Dietary Supplementation With omega3-fatty Acids (Fish Oil) and Progressive Resistance Training on Skeletal Muscle Status in Gynaecological, Gastrointestinal and Urological Cancer Patients