Actively Recruiting
Effects of Low-level Laser Therapy on Soft and Hard Tissue Healing After Impacted Mandibular Third Molar Extraction
Led by University of Medicine and Pharmacy at Ho Chi Minh City · Updated on 2025-11-28
22
Participants Needed
1
Research Sites
69 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Impacted lower third molar extraction is one of the most commonly performed dental procedures in daily practice. However, this is considered a relatively invasive procedure. During the surgery, dental surgeon must reflect a full-thickness flap, remove bone to expose the tooth, section and deliver the tooth. As a result, after surgery, patients often experience many complications, from swelling, pain, jaw tightness, etc. to alveolar bone loss, periodontal problems distal to the second molar, etc. Therefore, clinicians are always looking for additional therapies to minimize complications, helping patients have a more comfortable experience after wisdom tooth surgery. To date, placing grafting materials such as bone or other biological materials (growth factors, platelet-rich plasma, platelet-rich fibrin) into the tooth socket has been shown to be able to preserve the alveolar crest after extraction. However, these materials require preparation time, are costly, and have the risk of infection related to bone grafts. Meanwhile, low-level laser therapy (LLLT) is known as a safe, non-invasive therapy that can affect cell metabolism without causing tissue damage. This therapy has been widely applied in many fields of medicine in general and in dentistry in particular. Low-level lasers have been studied to help reduce swelling, pain, and jaw tightness after impacted lower wisdom teeth surgery. In vitro or in vivo studies evaluating the healing effect of low-level lasers have given very positive results. However, there is still a lack of scientific evidence to prove the healing effect of low-level lasers on human tooth extraction sockets. The study we conducted is a scientific study, in the field of Dentistry. This study aimed to evaluate the effectiveness of low-level laser on soft tissue and bone healing after surgical extraction of impacted lower third molars in a group of Vietnamese population.
CONDITIONS
Official Title
Effects of Low-level Laser Therapy on Soft and Hard Tissue Healing After Impacted Mandibular Third Molar Extraction
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Healthy patients at least 18 years old
- Patients with both lower impacted third molars recommended for extraction
- Both lower third molars are similar in condition
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
AI-Screening
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Trial Site Locations
Total: 1 location
1
University of medicine and pharmacy at Ho Chi Minh city
Ho Chi Minh City, Vietnam, 7000000
Actively Recruiting
Research Team
H
Hiep Hoang Ngoc Nguyen, Doctor of Dental Surgery
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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