Actively Recruiting

Age: 18Years - 75Years
All Genders
Healthy Volunteers
ID06624982

Determinants of Bone Dimensional Changes After Tooth Extraction and Alveolar Ridge Preservation

Led by Marquette University · Updated on 2025-11-17

160

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to understand how the immediate changes in the width of the tooth socket after extraction affect the bone ridge width and height four months later following alveolar ridge preservation. The study focuses on adult patients scheduled for tooth extraction with bone graft placement, investigating whether the socket expands or stays the same width immediately after extraction and how this relates to bone healing outcomes. Patients from the Graduate Periodontics Clinic at Marquette University School of Dentistry will be recruited for this observational study. Participants will undergo a single tooth extraction followed by alveolar ridge preservation using bone graft and a resorbable membrane. The study observes four groups based on tooth type (molar or non-molar) and whether the socket width expands immediately after extraction or remains unchanged. Measurements of ridge width and height, gingival thickness and width, and bone thickness will be recorded before extraction, immediately after, and at four months post-extraction. Other factors such as tooth mobility, root characteristics, extraction duration, and operator experience will also be documented. Throughout the study, participants will have several assessments including clinical measurements before and after extraction and at a four-month follow-up. Researchers will collect data on buccolingual ridge width and ridge height at three time points, gingival dimensions, and other clinical parameters. This information will help determine how immediate post-extraction socket conditions influence bone dimensional changes during healing. The total participation spans from initial consent through the four-month follow-up after alveolar ridge preservation.

CONDITIONS

Brief Title

Determinants of Bone Dimensional Changes After Extraction and Alveolar Ridge Preservation

Who Can Participate

Age: 18Years - 75Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patients aged 18 to 75 years
  • Good general health with controlled medical conditions
  • Controlled periodontal disease
  • Scheduled for single tooth extraction with bone graft placement and resorbable membrane
  • Tooth to be extracted has adjacent teeth
  • Intact socket wall integrity
Not Eligible

You will not qualify if you...

  • Current smokers
  • Pregnant individuals
  • Active periodontal disease
  • Systemic health conditions that affect healing
  • Lack of socket wall integrity (bone loss ≥50%) before extraction
  • Severe infection requiring antibiotics before extraction
  • Contraindications for tooth extraction

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person) for eligibility assessment

Diagnostic Evaluation

Duration - Single day on treatment day

Participants have measurements recorded before and immediately after tooth extraction and alveolar ridge preservation.

1 visit (in-person) including local anesthesia, extraction, and immediate measurements

Long-term Monitoring

Duration - 4 months

Participants return for follow-up measurements 4 months after extraction and alveolar ridge preservation to assess bone dimensional changes.

1 follow-up visit (in-person) at 4 months post-extraction

Trial Site Locations

Total: 1 location

1

Marquette University School of Dentistry Graduate Periodontics Clinic

Milwaukee, Wisconsin, United States, 53233

Actively Recruiting

Loading map...

Research Team

V

Vrisiis Kofina, DDS, MS

S

Samah Rady, DDS

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

4

Similar Trials

Assessment of the Efficacy and Safety of OROXID® Oral Soluti...

Tooth Extrusion

Actively Recruiting

1 location

Clinical Observational Study on Changes in Skin Physiologica...

Skin Barrier Function

Actively Recruiting

1 location

Prospective Observational Study of Perioperative Biomarkers ...

Breast Neoplasms

Actively Recruiting

1 location

Frequently Asked Questions

Have more questions? Get in touch with our team for quick support

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here