Actively Recruiting

Age: 18Years +
FEMALE
Healthy Volunteers
NCT00330447

Effects of Oncological Treatment During Pregnancy on Mother and Child

Led by University Hospital, Gasthuisberg · Updated on 2024-03-06

5000

Participants Needed

33

Research Sites

1426 weeks

Total Duration

On this page

Sponsors

U

University Hospital, Gasthuisberg

Lead Sponsor

T

The Netherlands Cancer Institute

Collaborating Sponsor

AI-Summary

What this Trial Is About

The researchers aim to investigate the outcome (overall survival) of mothers who are diagnosed and/or treated for cancer during pregnancy. Furthermore they want to test the hypothesis that children who were exposed to cancer or cancer treatment (cytotoxic drugs, radiation therapy, targeted therapy,...) develop normally (neurologic and cardiologic examination).

CONDITIONS

Official Title

Effects of Oncological Treatment During Pregnancy on Mother and Child

Who Can Participate

Age: 18Years +
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Histologically proven cancer associated with a pregnancy (diagnosed during pregnancy or within 5 years after pregnancy)
  • Female participants over 18 years of age and premenopausal
  • Signed and written informed consent provided after understanding the study
  • Women receiving any cytotoxic drug or radiation therapy during pregnancy allowed for maternal and fetal outcome assessment
  • Children prenatally exposed to cancer or cancer treatment with parental informed consent; assent from children aged 12 years or older
Not Eligible

You will not qualify if you...

  • Mentally disabled or significantly altered mental status preventing understanding and giving informed consent

AI-Screening

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Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 33 locations

1

Cooper University Hospital (2015-ongoing)

Camden, New Jersey, United States, 08103

Actively Recruiting

2

Instituto Alexander Fleming

Buenos Aires, Argentina

Withdrawn

3

Universitätsklinik für Frauenheilkunde und Geburtshilfe (retrospective 2016-2018)

Graz, Austria

Terminated

4

UCL Brussels (2013-ongoing)

Brussels, Belgium

Actively Recruiting

5

UZ Gasthuisberg, Katholieke Universiteit Leuven (2004-ongoing)

Leuven, Belgium, 3000

Actively Recruiting

6

University Hospital Ostrava (2018-ongoing)

Ostrava, Czechia

Actively Recruiting

7

3rd medical faculty of Charles University (2010-ongoing)

Prague, Czechia

Actively Recruiting

8

Copenhagen University Hospital (2015-ongoing)

Copenhagen, Denmark

Actively Recruiting

9

Hopital Bichat-Claude-Bernard (retrospective until 2018)

Paris, France

Terminated

10

Universitätsklinik Freiburg (retrospective until 2018)

Freiburg im Breisgau, Germany

Terminated

11

Euroclinic Hospital (2016-ongoing)

Athens, Greece

Actively Recruiting

12

Hellenic Anticancer-Oncological Hospital of Athens (retrospective 2015-2018)

Athens, Greece

Terminated

13

Ioannina University Hospital (retrosepctive 2015-2018)

Ioannina, Greece

Terminated

14

Hippokration Hospital (retrospective 2015-2018)

Thessaloniki, Greece

Terminated

15

European Institute of Oncology (2010-ongoing)

Milan, Italy

Actively Recruiting

16

Fondazione IRCCS Ca'Granda Ospedale Maggiore (2012-ongoing)

Milan, Italy

Actively Recruiting

17

Fondazione IRCCS Ca'Granda Ospedale Maggiore Policlinico Milano (2017-ongoing)

Milan, Italy

Actively Recruiting

18

San Raffaele Hospital (2017-ongoing)

Milan, Italy

Actively Recruiting

19

CIttà della Salute e della Scienza di Torino (2015-ongoing)

Torino, Italy

Actively Recruiting

20

Regional Hospital of High Specialty of Ixtapaluca (2018-ongoing)

Ixtapaluca, Mexico, 56530

Actively Recruiting

21

Erasmus Medical Center (2014-ongoing)

Rotterdam, Netherlands

Actively Recruiting

22

Haukeland University Hospital (2017-ongoing)

Bergen, Norway

Actively Recruiting

23

Medyczne Macierzynstwo (retrospective 2010-2018)

Krakow, Poland

Terminated

24

University Hospital Krakow (2018-ongoing)

Krakow, Poland

Actively Recruiting

25

Pozanan University of Medical Sciences (2017-ongoing)

Poznan, Poland

Actively Recruiting

26

Hospital de Vila Franca de Xira (2017-ongoing)

Vila Franca de Xira, Portugal

Actively Recruiting

27

N.N.Blokchin National Medical Research Center of Oncology (2013-2018 retrospective; 2018-ongoing prospective)

Moscow, Russia

Actively Recruiting

28

Research Center for Obstetrics, Gynecology and Perinatology (2014-ongoing)

Moscow, Russia

Actively Recruiting

29

Almazov National Medical Research Center (2018-ongoing)

Saint Petersburg, Russia

Actively Recruiting

30

Karolinska University Hospital (2017-ongoing)

Stockholm, Sweden

Actively Recruiting

31

F.Hached University Teaching Hospital (retrospective 2016-2018)

Sousse, Tunisia

Terminated

32

Trakya University Faculty of Medicine (retrospective 2015-2018)

Edirne, Turkey (Türkiye)

Terminated

33

Grigoriev Institute for medical Radiology (retrospective until 2018)

Kharkiv, Ukraine

Terminated

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Research Team

A

Ayaka Wakatsuki

CONTACT

K

Kristel Van Calsteren, MD PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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Effects of Oncological Treatment During Pregnancy on Mother and Child | DecenTrialz