Actively Recruiting

Phase Not Applicable
Age: 18Years +
FEMALE
Healthy Volunteers
NCT06571721

The Effects of Topical Almond Oil and Tretinoin on Facial Wrinkles

Led by Integrative Skin Science and Research · Updated on 2024-08-28

90

Participants Needed

1

Research Sites

52 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Investigate the topical use of almond oil, almond oil augmented with 0.5% vitamin E, 0.025% tretinoin oil augmented with castor oil on the appearance of facial fine lines and wrinkles, pigmentation, hydration, trans-epidermal water loss, and sebum excretion rate.

CONDITIONS

Official Title

The Effects of Topical Almond Oil and Tretinoin on Facial Wrinkles

Who Can Participate

Age: 18Years +
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Post-menopausal women of Fitzpatrick skin types 1, 2, and 3
  • Individuals with facial fine lines and wrinkles
Not Eligible

You will not qualify if you...

  • Pregnancy or breastfeeding
  • Prisoners
  • Adults unable to consent
  • Allergy to nuts or tocopherol (vitamin E)
  • Current smokers, those who smoked within the past year, or former smokers with over a 10-pack-year history
  • Autoimmune photosensitive conditions or genetic collagen deficiency disorders such as Ehlers-Danlos syndrome
  • Cosmetic facial procedures within 3 months prior to enrollment or deep chemical peels within 1 year prior
  • Unwillingness to stop vitamin E supplements and foods like nuts, sunflower seeds, or sunflower oil during the study
  • Unwillingness to stop use of topical cosmetics that affect collagen or pigmentation during the study, including retinoids, antioxidants like vitamin C or E, pigment reducers such as hydroquinone, azelaic acid, kojic acid, and topical products containing nut oils or extracts

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Integrative Research Institute

Sacramento, California, United States, 95819

Actively Recruiting

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Research Team

N

Nasima Afzal

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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