Actively Recruiting

Age: 18Years +
All Genders
NCT05282108

Efficacy and Safety of Generic Imatinib (Carcemia®) Compared to Glivec® in Real-Life Management of Chronic Phase of Chronic Myeloid Leukemia

Led by Hikma Pharmaceuticals LLC · Updated on 2025-03-26

240

Participants Needed

4

Research Sites

223 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to evaluate Efficacy and Safety of Generic Imatinib (Carcemia®) Compared to Glivec® in Real-Life Management of Chronic Phase of Chronic Myeloid Leukemia

CONDITIONS

Official Title

Efficacy and Safety of Generic Imatinib (Carcemia®) Compared to Glivec® in Real-Life Management of Chronic Phase of Chronic Myeloid Leukemia

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Newly diagnosed with Philadelphia chromosome-positive Chronic Myeloid Leukemia in the chronic phase
  • Diagnosis confirmed within 3 months before enrollment and not yet treated
  • Liver aminotransferases and serum bilirubin levels at or below 2 times the upper normal limit
  • Serum creatinine at or below 1.5 times the upper normal limit
  • Provided written informed consent
Not Eligible

You will not qualify if you...

  • Accelerated phase Chronic Myeloid Leukemia at enrollment, except if with other cytogenetic abnormalities at diagnosis
  • Blast phase Chronic Myeloid Leukemia at enrollment
  • Any contraindications to the study drug according to its approved product information

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 4 locations

1

National Cancer Institute (NCI)

Cairo, Egypt, 11796

Actively Recruiting

2

Ain Shams University Hospital

Cairo, Egypt

Not Yet Recruiting

3

Nasser Institute

Cairo, Egypt

Actively Recruiting

4

Tanta Oncology Center

Tanta, Egypt

Not Yet Recruiting

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Research Team

R

Ruba A Jaber

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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Efficacy and Safety of Generic Imatinib (Carcemia®) Compared to Glivec® in Real-Life Management of Chronic Phase of Chronic Myeloid Leukemia | DecenTrialz