Study of Pulsed Radiofrequency Combined with Platelet Rich Plasma for Treating Idiopathic Glossopharyngeal Neuralgia

What this Trial Is About

Researchers are evaluating the effectiveness and safety of combining Pulsed Radiofrequency PRF with Platelet Rich Plasma PRP to treat idiopathic Glossopharyngeal Neuralgia GPN, a type of nerve pain. This observational study aims to compare treatment outcomes between patients receiving only PRF and those receiving PRF combined with PRP, focusing on pain relief and safety. During the study, participants receive motor stimulation at 2 Hz and 1.0V to confirm no muscle contraction before undergoing PRF treatment lasting 360 seconds at specific settings 45 V, 42C, 2 Hz pulse rate. One group receives only PRF, while the other group also receives a slow injection of 2 ml of leukocyte-poor PRP mixture after PRF. Additional pain relief medication is available as needed. If pain relief is unsatisfactory after one month, other treatments are offered. Participants will be assessed using the Numeric Rating Scale NRS to measure pain at multiple time points 1 day, 3 days, 1 week, 2 weeks, 1 month, 3 months, 6 months, and 1 year after treatment. The Barrow Neurological Institute pain scale BNI is also used at these times to evaluate pain. The study includes follow-up for at least one month and monitors safety through medical records and clinical evaluations throughout the study period.

Efficacy and Safety of Pulsed Radiofrequency Combined With Platelet Rich Plasma to Treat Idiopathic Glossopharyngeal Neuralgia (GPN)