Actively Recruiting
Efficacy and Safety of Telitacicept Combined With Baricitinib for Refractory Rheumatoid Arthritis
Led by Zhejiang Provincial People's Hospital · Updated on 2026-03-30
30
Participants Needed
1
Research Sites
108 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The aim of this study is to observe the clinical efficacy and safety of telitacicept combined with baricitinib in the treatment of D2TRA patients
CONDITIONS
Official Title
Efficacy and Safety of Telitacicept Combined With Baricitinib for Refractory Rheumatoid Arthritis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18-85 years
- Diagnosed with refractory rheumatoid arthritis according to the 2021 EULAR diagnostic criteria
- Traditional disease-modifying rheumatic drug treatments have been ineffective
- Use of two or more biological or targeted disease-modifying anti-rheumatic drugs has been ineffective
- Patients require treatment with telitacicept combined with tofacitinib
- Voluntary written informed consent provided
You will not qualify if you...
- Severe diseases of major organs such as heart, liver, or lungs
- Malignancies, blood disorders, or other autoimmune diseases besides rheumatoid arthritis
- History of allergy or hypersensitivity to telitacicept or tofacitinib
- Active tuberculosis or infectious diseases needing systemic treatment
- Pregnancy, breastfeeding, or refusal to use contraception during the study
- Failure to complete the telitacicept and tofacitinib treatment due to non-adherence or severe side effects
- Other conditions that the investigator judges as reasons for exclusion
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Zhejiang Provincial People's Hospital
Hangzhou, Zhejiang, China, 310000
Actively Recruiting
Research Team
Z
Zhenhua Ying
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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