Actively Recruiting
Efficacy and Safety of Telitacicept Combined With Tofacitinib for Refractory Rheumatoid Arthritis
Led by Zhejiang Provincial People's Hospital · Updated on 2025-05-18
20
Participants Needed
1
Research Sites
99 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The aim of this study is to observe the clinical efficacy and safety of telitacicept combined with tofacitinib in the treatment of D2TRA patients
CONDITIONS
Official Title
Efficacy and Safety of Telitacicept Combined With Tofacitinib for Refractory Rheumatoid Arthritis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18-85 years
- Diagnosed with refractory rheumatoid arthritis based on the 2021 EULAR diagnostic criteria
- Traditional disease-modifying anti-rheumatic drugs treatment ineffective
- Ineffective use of two or more biological or targeted anti-rheumatic drugs
- Require treatment with telitacicept combined with tofacitinib
- Voluntarily provided written informed consent
You will not qualify if you...
- Severe diseases of major organs such as heart, liver, or lungs
- Malignancies, blood disorders, or other autoimmune diseases excluding rheumatoid arthritis
- History of allergy or hypersensitivity to telitacicept or tofacitinib
- Active tuberculosis or active infectious diseases requiring systemic treatment
- Pregnancy, breastfeeding, or refusal to use contraception during the study
- Failure to complete the prescribed telitacicept and tofacitinib treatment due to non-adherence or severe adverse reactions
- Other conditions preventing participation as judged by the investigator
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Zhejiang Provincial People's Hospital
Hangzhou, Zhejiang, China, 310000
Actively Recruiting
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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