Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
NCT06566651

Emotion Processing Among Patients With ALS

Led by University of Aarhus · Updated on 2024-08-22

180

Participants Needed

2

Research Sites

132 weeks

Total Duration

On this page

Sponsors

U

University of Aarhus

Lead Sponsor

A

Aarhus University Hospital

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this observational study is to learn about the emotional perception in people with ALS disease compared to people with other neuromuscular disease and healthy controls. The main questions it aims to answer are: * How people with ALS judge happy and angry faces and what their "insight" into these judgements are like * How their autonomic responses differ from the other two test group Participants will asked to judge if a face presents a happy emotion or angry emotion. Researchers will compare the ALS group responses with neuromuscular diseases group and healthy control group responses to see if the ALS group judge more happy faces than angry.

CONDITIONS

Official Title

Emotion Processing Among Patients With ALS

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • ALS patients, ambulant and hospitalized, able to give informed consent, diagnosed with ALS or probable ALS according to the El Escorial Criteria
  • Patients with a peripheral neuromuscular disease, ambulant and hospitalized, able to give informed consent, diagnosed with a peripheral neuromuscular disease not affecting the central nervous system, including but not limited to Myasthenia Gravis and polyneuropathy
  • Healthy controls, able to give informed consent, age and gender matched to ALS patients
Not Eligible

You will not qualify if you...

  • Other severe medical, neurological, or psychiatric disorders
  • Visual impairment interfering with the ability to perform the test
  • Severe motor or cognitive deficits preventing test performance
  • Alcohol or drug abuse interfering with task performance
  • For patients with peripheral neuromuscular disease: familial predisposition to ALS
  • For healthy controls: familial predisposition to ALS (first degree relatives), medical treatment affecting the central nervous system (e.g., antidepressants)

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 2 locations

1

Aarhus University Hospital

Aarhus, Central Jutland, Denmark, 8200

Actively Recruiting

2

Aalborg University Hospital

Aalborg, Region Nordjulland, Denmark, 9000

Not Yet Recruiting

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Research Team

M

Mia B Heintzelmann, Cand.med

CONTACT

C

Camilla Hakala, Bach.psych

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

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