Study of Safety and Effectiveness of Endoscopic Removal of Cancer and Precancerous Lesions in the Digestive Tract
Led by Azienda USL Reggio Emilia - IRCCS · Updated on 2025-10-03
2000
Participants Needed
1
Research Sites
N/A
Total Duration
AI-Summary
What this Trial Is About
Researchers are investigating endoscopic removal procedures for cancerous and precancerous lesions in the upper and lower digestive tract. The study aims to evaluate the safety and effectiveness of different resection techniques, including mucosectomy, en bloc and piecemeal resection, endoscopic submucosal dissection ESD and its variants, and full-thickness resection. The anatomical areas studied include the esophagus, stomach, duodenum, colon, and rectum.
The procedures studied involve various endoscopic resection methods used to remove lesions from the digestive tract. Techniques include endoscopic mucosal resection EMR for mucosal lesions, endoscopic submucosal dissection for larger or submucosal lesions, and full-thickness resection for infiltrating lesions involving the entire gastrointestinal wall. These methods are compared to assess their efficacy and safety.
Participants who previously underwent endoscopic resection will have their medical records retrospectively reviewed. Researchers will analyze outcomes such as the rate of en bloc resection, complete removal of lesions, and recurrence within one year. They will also assess adverse events and costs within one month. The studys observational nature means no new treatments are given, and the total participation involves data analysis from past procedures.
CONDITIONS
Brief Title
Endoscopic Resection of Gastrointestinal Neoplasms
Research Team
P
Paolo Cecinato, MD
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Patients who have undergone endoscopic resection of an upper or lower digestive tract tumor
You will not qualify if you...
Under 18 years of age
Unable to provide informed consent
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Implementation
Duration - Procedure day
Participants undergo an endoscopic resection procedure to remove cancerous or precancerous lesions of the digestive tract.
1 visit (in-person)
Post-operative Follow-up
Duration - Up to 1 year
Participants are monitored for safety and treatment outcomes following endoscopic resection.
Approximately 3 visits over 1 year
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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Published Research Related To This Trial
Left colonic localization, non-granular morphology, and pit pattern independently predict submucosal fibrosis of naïve colorectal neoplasms before endoscopic submucosal dissection.
Paolo Cecinato, Andrea Lisotti, Francesco Azzolini...