Actively Recruiting

Age: 18Years - 100Years
All Genders
ID04780256

Retrospective Study of Efficacy and Safety of the Endoscopic Removal of Cancerous and Precancerous Lesions of the Upper and Lower Digestive Tract

Led by Azienda USL Reggio Emilia - IRCCS · Updated on 2025-10-03

2000

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are investigating endoscopic removal procedures for cancerous and precancerous lesions in the upper and lower digestive tract. The study aims to evaluate the safety and effectiveness of different resection techniques, including mucosectomy, en bloc and piecemeal resection, endoscopic submucosal dissection (ESD) and its variants, and full-thickness resection. The anatomical areas studied include the esophagus, stomach, duodenum, colon, and rectum. The procedures studied involve various endoscopic resection methods used to remove lesions from the digestive tract. Techniques include endoscopic mucosal resection (EMR) for mucosal lesions, endoscopic submucosal dissection for larger or submucosal lesions, and full-thickness resection for infiltrating lesions involving the entire gastrointestinal wall. These methods are compared to assess their efficacy and safety. Participants who previously underwent endoscopic resection will have their medical records retrospectively reviewed. Researchers will analyze outcomes such as the rate of en bloc resection, complete removal of lesions, and recurrence within one year. They will also assess adverse events and costs within one month. The study's observational nature means no new treatments are given, and the total participation involves data analysis from past procedures.

CONDITIONS

Brief Title

Endoscopic Resection of Gastrointestinal Neoplasms

Who Can Participate

Age: 18Years - 100Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • 18 years or older
  • Patients who have undergone endoscopic resection of an upper or lower digestive tract tumor
Not Eligible

You will not qualify if you...

  • Under 18 years of age
  • Unable to provide informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Implementation

Duration - Procedure day

Participants undergo an endoscopic resection procedure to remove cancerous or precancerous lesions of the digestive tract.

1 visit (in-person)

Post-operative Follow-up

Duration - Up to 1 year

Participants are monitored for safety and treatment outcomes following endoscopic resection.

Approximately 3 visits over 1 year

Trial Site Locations

Total: 1 location

1

IRCCS-AUSL Reggio Emilia

Reggio Emilia, RE, Italy

Actively Recruiting

Loading map...

Research Team

P

Paolo Cecinato, MD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

Similar Trials

A Phase I/II Trial of UCB4594 to Assess Safety, Pharmacokine...

Advanced Solid Tumours

Actively Recruiting

4 locations

A Phase 1a/b Open-Label Trial Evaluating LY4257496, a GRPR-T...

Breast Neoplasms

Actively Recruiting

30 locations

A Dose Escalation and Dose Optimization Phase 1a/1b Study to...

Ovarian Neoplasms

Actively Recruiting

30 locations

Frequently Asked Questions

Have more questions? Get in touch with our team for quick support

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here

Published Research Related To This Trial

Left colonic localization, non-granular morphology, and pit pattern independently predict submucosal fibrosis of naïve colorectal neoplasms before endoscopic submucosal dissection.

Paolo Cecinato, Andrea Lisotti, Francesco Azzolini...

https://pubmed.ncbi.nlm.nih.gov/36542136