Actively Recruiting

All Genders
NCT07369414

Environmental Reservoirs of Non-tuberculous Mycobacteria in Cystic Fibrosis Households: A Case-control Study of Exposure Risk at Home

Led by Research Center Borstel · Updated on 2026-01-27

120

Participants Needed

2

Research Sites

256 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This multicenter, non-interventional case-control study investigates whether household environmental reservoirs, particularly water systems, are associated with non-tuberculous mycobacterial (NTM) infections in people with cystic fibrosis. Environmental samples from the homes of CF patients with and without NTM infection will be analyzed and genetically compared with available clinical isolates, alongside assessment of environmental risk factors, to improve understanding of exposure pathways and inform future prevention strategies.

CONDITIONS

Official Title

Environmental Reservoirs of Non-tuberculous Mycobacteria in Cystic Fibrosis Households: A Case-control Study of Exposure Risk at Home

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Confirmed diagnosis of cystic fibrosis (CF)
  • No age restriction (including minors with consent from legal guardians)
  • Written informed consent to participate in the study (or consent provided by a legal guardian for minors)
  • For those with NTM infection: diagnosis according to ATS/IDSA criteria and availability of a clinical NTM isolate
Not Eligible

You will not qualify if you...

  • Lack of capacity to provide informed consent, refusal to participate, or withdrawal of informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

National and WHO-Supranational Reference Center for Mycobacteria, Research Center Borstel, Leibniz Lung Center

Borstel, Schleswig-Holstein, Germany, 23845

Actively Recruiting

2

Klinik für Pneumologie, Universitätsklinikum Essen

Essen, Germany

Not Yet Recruiting

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Research Team

M

Margo Diricks, PhD

CONTACT

N

Niklas Koehler, Dr. med.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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