Actively Recruiting
Epigenetics and Prevention of Non-communicable Diseases in Kazakhstan: a Personalized Approach and Biological Age Prediction
Led by Asfendiyarov Kazakh National Medical University · Updated on 2025-07-11
6720
Participants Needed
1
Research Sites
52 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are exploring ways to improve personalized and preventive care for non-communicable diseases such as cardiovascular diseases, type 2 diabetes, chronic respiratory diseases, obesity, and chronic kidney diseases in Kazakhstan. This observational study focuses on understanding epigenetic factors and uses machine learning models to predict biological age and reproductive function, aiming to tailor health recommendations for individuals. The study involves one cohort divided into four age groups: 18-29 years, 30-44 years, 45-59 years, and 60-69 years, with an equal number of men and women in each group. Participants will undergo genetic investigations including DNA analysis to examine telomere length and DNA methylation levels. Data collection and model predictions will take place within ten months from the start of the study. Participants will be residents of Kazakhstan aged 18 to 69 years who consent to participate. The study will monitor the accuracy of machine learning models in predicting biological age and reproductive function. All data collection will be observational, with no treatments administered. The total participation timeline includes data collection and assessment periods within the planned study duration ending in 2026.
CONDITIONS
Brief Title
Epigenetics and NCD Prevention in Kazakhstan: Personalized Approaches and Biological Age Prediction
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 to 69 years
- Residents of 17 regions of Kazakhstan
- Willingness to participate and provide informed consent
You will not qualify if you...
- Age less than 18 years old or over 69 years old
- Failure to provide informed consent or incomplete participation in data collection procedures
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Within 10 months from start of data collection
Participants undergo genetic DNA analysis including investigation of telomere length and DNA methylation levels to assess biological age and reproductive function.
Trial Site Locations
Total: 1 location
1
Asfendiyarov Kazakh National Medical University
Almaty, Kazakhstan, Kazakhstan, 050000
Actively Recruiting
Research Team
I
Ildar Fakhradiyev, Ph.D
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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