Comparing Erector Spinae Block and Paravertebral Block to Reduce Chronic Pain After Mastectomy A Randomized Study in Adults Aged 18 to 80

What this Trial Is About

Researchers are evaluating the erector spinae block ESB compared to the paravertebral block PVB to see if ESB can reduce the occurrence of chronic pain three months after total mastectomy in adults aged 18 to 80 years. This study aims to determine whether ESB provides equivalent or improved outcomes in chronic pain and other postoperative measures such as opioid use, pain scores, and psychological effects like anxiety or depression. The trial is a prospective randomized clinical study conducted at a medical center. Participants will be randomly assigned to receive either the erector spinae block or the paravertebral block before undergoing total mastectomy, with or without axillary dissection. The paravertebral block is performed using ultrasound guidance to inject ropivacaine near the spinal nerves at specific thoracic levels. The erector spinae block involves injecting ropivacaine at similar thoracic levels but targets a different muscle area, also under ultrasound guidance. Both procedures use carefully measured doses of local anesthetic. During the study, participants will have their pain levels assessed immediately after surgery in the recovery area and at 24 and 48 hours postoperatively. Opioid consumption will be recorded for the first 48 hours after surgery. Researchers will also measure the time needed to perform each block, monitor for complications, and evaluate anxiety or depression along with pain intensity at three months after surgery. The main outcome is the incidence of chronic pain at three months following mastectomy.

Erector Spinae Block Versus Paravertebral Block on Chronic Pain After Mastectomy