Actively Recruiting
Evaluation of Erythropoietin Gel Effect on Stability of Immediate Dental Implants After Tooth Extraction in the Anterior Maxilla
Led by Al-Azhar University · Updated on 2026-05-18
24
Participants Needed
1
Research Sites
4 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are investigating how coating dental implants with erythropoietin gel affects the stability of immediate implants placed after tooth extraction in the front upper jaw (anterior maxilla). This study aims to improve and speed up the integration of dental implants with bone, known as osseointegration, which is vital for long-term implant success. The trial is randomized and controlled to compare coated and non-coated implants. Participants in this study will be randomly assigned to one of two groups. One group will receive dental implants coated with erythropoietin gel immediately after tooth extraction, while the other group will receive non-coated implants under the same conditions. The focus is on implants placed right after removing non-restorable teeth in the anterior maxilla. During the study, researchers will measure implant stability at the time of placement and again after six months. They will also assess the bone level and density around the implants using clinical and radiographic methods. The study's total observation period for each participant is six months, during which safety and implant integration will be closely monitored.
CONDITIONS
Brief Title
Erythropoietin Gel Effect on Dental Implant Stability
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients must have non-restorable teeth in the anterior maxilla needing extraction and implant placement.
- Patients must have good general periodontal health and maintenance.
- Age between 20 and 50 years.
- Both male and female patients are eligible.
You will not qualify if you...
- Heavy smokers who smoke more than ten cigarettes per day.
- Presence of acute infected socket.
- Extraction socket with wall defect.
- Pregnancy.
- Local or systemic conditions interfering with bone healing such as uncontrolled diabetes, HIV infection, or bone disorders like hyperparathyroidism, osteoporosis, or Paget's disease.
- Patients who have received intravenous or oral bisphosphonate therapy.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - 6 months
Participants receive immediate dental implants in the anterior maxilla, either coated with erythropoietin gel or non-coated.
1 baseline visit and 1 follow-up visit
Trial Site Locations
Total: 1 location
1
Faculty of dental medicine Al-Azhar university
Asyut, Asyut Governorate, Egypt, 088
Actively Recruiting
Research Team
A
Ahmed Mohsen Principle investigator
M
Mohamed Mahjob Head of oral and maxillofacial surgery department
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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