Anisocoria After Direct Light Stimulus is Associated with Poor Outcomes Following Acute Brain Injury.
Brittany R Doyle, Venkatesh Aiyagari, Shoji Yokobori...
https://pubmed.ncbi.nlm.nih.gov/38918339/Actively Recruiting
Led by University of Texas Southwestern Medical Center · Updated on 2025-10-22
1000
Participants Needed
1
Research Sites
N/A
Total Duration
Researchers are gathering extensive data to better understand pupillometer readings in patients admitted to intensive care units. The study aims to develop standard reference values for pupil size, reaction, and neurological pupil index based on automated pupillary exams. This will help define what normal pupil measurements look like in a clinical setting. Data collection involves patients in intensive care who have been ordered by their attending physicians to undergo regular pupillary assessments using a pupillometer device. Nurses perform these assessments routinely. The project plans to collect a large number of observations to accurately describe the normal range of pupillary exam results. During the study, participants will have daily oculomotor evaluations measuring pupillary changes during their ICU stay, recorded each day at 900am. This observational approach helps researchers analyze pupil data over time to better understand neurological function. The study will continue to gather data until September 2028.
CONDITIONS
Establishing Normative Data for Pupillometer Assessments in Neuro-Intensive Care
D
DaiWai M Olson, PhD
M
Maria E Denbow
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here
University of Texas Southwestern Medical Center
Lead Sponsor
NeurOptics Inc
Collaborating Sponsor
You may qualify if you...
You will not qualify if you...
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Duration of ICU admission
Participants who have routine pupillary assessments performed by staff nurses using a pupillometer are observed to collect data on pupillary variance during ICU admission.
Daily visits at 9:00am for pupillary assessments
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
Have more questions? Get in touch with our team for quick support
Brittany R Doyle, Venkatesh Aiyagari, Shoji Yokobori...
https://pubmed.ncbi.nlm.nih.gov/38918339/Yesica Andrea Campos, Priyanka Rana, Ranier G Reyes...
https://pubmed.ncbi.nlm.nih.gov/35776519/Claudio M Privitera, Sanjay V Neerukonda, Venkatesh Aiyagari...
https://pubmed.ncbi.nlm.nih.gov/35869429/Barsha Thakur, Hend Nadim, Folefac Atem...
https://pubmed.ncbi.nlm.nih.gov/33347373/University of Texas Southwestern Medical Center
Lead Sponsor
NeurOptics Inc
Collaborating Sponsor