Actively Recruiting
Estimation of the Diaphragm Electrical Activity and Intercostal Thickening Fraction During Different Pattern of Mechanical Ventilation: PSV Versus NAVA
Led by Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Updated on 2024-10-18
20
Participants Needed
1
Research Sites
169 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
the introduction of new MV modalities has shown promising results in reducing the incidence of weaning failure, mainly due to a more physiologic approach which allows respiratory muscle preservation. Among them, the Neurally Adjust Ventilatory Assist (NAVA) seemed to be associated with lower incidence of weaning failure and subsequent duration of mechanical ventilation, compared to standard modalities like the Pressure Support Ventilation (PSV) . Moreover, NAVA allows the evaluation of the diaphragm electrical activity (EAdi), an index of diaphragmatic neural respiratory drive. However, no study has compared TFic values during PSV and NAVA modalities in patients with difficult weaning from MV admitted in ICU.
CONDITIONS
Official Title
Estimation of the Diaphragm Electrical Activity and Intercostal Thickening Fraction During Different Pattern of Mechanical Ventilation: PSV Versus NAVA
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients who have failed at least one weaning attempt
- Mechanical ventilation for at least 24 hours
You will not qualify if you...
- Pregnancy
- Obesity (Body Mass Index > 35 kg/m2)
- Contraindication to the insertion of a nasogastric tube
- Neuromuscular diseases
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Giorgia Spinazzola
Rome, Italy, 00168
Actively Recruiting
Research Team
G
giorgia GS spinazzola, md
CONTACT
G
gianmarco gm maresca, md
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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