Endothelial Dysfunction in Youth-Onset Type 2 Diabetes: A Clinical Translational Study.
Khaled Z Abd-Elmoniem, Jehad H Edwan, Katrina B Dietsche...
https://pubmed.ncbi.nlm.nih.gov/39069898Actively Recruiting
Age: 18Years - 100Years
All Genders
Healthy Volunteers
ID02830308
Evaluation of Adults With Endocrine-Related Conditions
Led by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) · Updated on 2026-05-12
1250
Participants Needed
1
Research Sites
1 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying adults with known or suspected endocrine or metabolic conditions, such as diabetes and thyroid diseases, which sometimes arise from genetic changes. The goal is to better understand these disorders and to train doctors in diagnosing and treating hormone-related gland problems. This observational study collects detailed health data to increase knowledge about these diseases. Participants undergo a medical history review and physical examination. Most will have one visit, with possible follow-ups as needed. Tests may include blood, urine, and saliva samples; imaging like X-rays or ultrasounds; sleep studies; and medical photographs. Samples may be stored for future research, including genetic testing. Additional specialist visits might be part of the evaluation. During the study, participants provide various biological samples and undergo assessments such as vital signs and endocrine lab studies. Researchers track participants' diagnosis, management, treatment, and follow-up experiences. The study aims to recruit a diverse adult group and may involve multiple visits over time to collect comprehensive data. Participation can include samples and information storage for future studies.
CONDITIONS
Brief Title
Evaluation of Adults With Endocrine and Metabolic-Related Conditions
Who Can Participate
Age: 18Years - 100Years
All Genders
Healthy Volunteers
Eligibility Criteria
You may qualify if you...
- Participants with known or suspected endocrine disorder age 18 years and older are eligible for this protocol.
- Relatives ages 18 years and older may be enrolled if clinically indicated for the diagnosis of a proband.
- Protocol investigators will select subjects most appropriate for clinical evaluation.
You will not qualify if you...
- Anyone under the age of 18 years old.
- Medical, physical, psychiatric, or social conditions that would make participation not in the subject's best interest.
- Subjects who are critically ill, unstable, or with severe organ failure affecting endocrine evaluation or placing unsustainable demands on resources.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
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Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Diagnostic Evaluation
Duration - Duration varies based on clinical evaluation needs
Participants undergo history and physical exam, anthropometrics, vital signs, and endocrine laboratory studies to collect data related to endocrine or metabolic disorders.
1 to 2 visits depending on clinical evaluation
Long-term Monitoring
Duration - Up to several years depending on clinical follow-up
Participants with known or suspected endocrine or metabolic disorders are observed for ongoing data collection and follow-up.
Additional visits as clinically indicated
Trial Site Locations
Total: 1 location
1
National Institutes of Health Clinical Center
Bethesda, Maryland, United States, 20892
Actively Recruiting
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Research Team
M
Marissa F Lightbourne, M.D.
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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