Actively Recruiting
Evaluation of Children With Endocrine and Metabolic-Related Conditions
Led by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) · Updated on 2026-04-24
15000
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying children with known or suspected endocrine or metabolic disorders to better understand these conditions and their inheritance. This observational study aims to identify genes involved in these disorders, which could help improve diagnosis and treatment. The study is sponsored by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) and focuses on pediatric endocrine diseases across diverse populations. Participants include children aged 3 months to 18 years with endocrine or metabolic conditions, along with family members aged 3 months to 100 years who may join for genetic testing. The study involves reviewing medical records, clinical exams, and various tests such as blood, urine, saliva, growth hormone assessments, imaging (X-rays, ultrasound, scans), genetic testing, sleep studies, and medical photography. Some children may undergo surgery or other procedures as part of their diagnosis or treatment, with tissue samples taken if surgery occurs. During the study, children may have follow-up visits for ongoing diagnosis and treatment. Family members have a single visit for medical history and DNA sample collection. Researchers will monitor the number and diversity of endocrine diagnoses and collect genetic samples. The study involves comprehensive assessments and monitoring to better understand the natural progress and management of pediatric endocrine disorders, with participation lasting as needed for diagnosis and treatment.
CONDITIONS
Brief Title
Evaluation of Children With Endocrine and Metabolic-Related Conditions
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participants with known or suspected endocrine disorder aged 3 months to 18 years are eligible.
- Relatives aged 3 months to 100 years may be enrolled if clinically indicated for diagnosis.
You will not qualify if you...
- Individuals without suspected endocrine disorders are excluded.
- Those with medical, physical, psychiatric, or social conditions that may make participation unsafe or unsuitable are excluded.
- Patients who are critically ill, unstable, or have severe organ failure limiting endocrine evaluation are excluded.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Varies based on clinical needs
Participants undergo standard clinically indicated laboratory or radiological studies to confirm diagnosis or aid in management of endocrine or metabolic conditions.
1 to 2 visits depending on clinical indication
Duration - Ongoing as determined by clinical management
Participants with known or suspected endocrine or metabolic disorders are observed over time to track the natural progress of their condition.
Follow-up visits as clinically indicated
Trial Site Locations
Total: 1 location
1
National Institutes of Health Clinical Center
Bethesda, Maryland, United States, 20892
Actively Recruiting
Research Team
H
Harinder D Raipuria, C.R.N.P.
C
Catherine M Gordon, M.D.
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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