Actively Recruiting
Evaluation of Children With Endocrine and Metabolic-Related Conditions
Led by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) · Updated on 2026-04-24
15000
Participants Needed
1
Research Sites
755 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Background: Endocrine glands give off hormones. Researchers want to learn more about the disorders that affect these glands in children. These disorders might be caused by changes in genes. Genes contain DNA, which is the blueprint of how a cell works. Researchers want to identify the genes involved in endocrine and metabolic disorders. This might help develop new ways to diagnose and treat the disorders. Objective: To study the inheritance of endocrine or metabolism disorders. Eligibility: Children ages 3month-18 with known or suspected endocrine or metabolism disorders. Family members ages 3months-100. They may participate in the DNA part of the study. Design: Participants will be screened with a review of their medical records. Their parents or guardians will allow the records to be released. Participants will have a clinic visit. This may include a physical exam and medical history. Parents or guardians will give their consent for the study. Participants may have tests, surgery, or other procedures to help diagnose or treat their condition. These could include: Blood, urine, and saliva tests Growth hormone test Pituitary and adrenal function tests Picture of chromosomes Imaging tests. These may include X-ray, ultrasound, scans, or a skeletal survey. Genetic tests Sleep study Medical photographs If surgery is done, a tissue sample will be taken. Participants may have follow-up visits for diagnosis and treatment. Participating relatives will have one visit. This will include medical history and blood and saliva tests. The blood and saliva will be used for DNA testing.
CONDITIONS
Official Title
Evaluation of Children With Endocrine and Metabolic-Related Conditions
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participants with known or suspected endocrine disorder aged 3 months to 18 years are eligible.
- Relatives aged 3 months to 100 years may be enrolled if clinically indicated for diagnosis of a proband.
You will not qualify if you...
- Lack of suspected endocrine disorders.
- Medical, physical, psychiatric, or social conditions that make participation not in the patient's best interest.
- Critically ill, unstable patients or those with severe organ failure limiting endocrine evaluation or placing unsustainable demands on resources.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
National Institutes of Health Clinical Center
Bethesda, Maryland, United States, 20892
Actively Recruiting
Research Team
H
Harinder D Raipuria, C.R.N.P.
CONTACT
C
Catherine M Gordon, M.D.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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