Actively Recruiting
Evaluation of Macroscopic Muscle Growth in Infants and Young Children With Spastic Cerebral Palsy
Led by Universitaire Ziekenhuizen KU Leuven · Updated on 2026-02-12
229
Participants Needed
1
Research Sites
407 weeks
Total Duration
On this page
Sponsors
U
Universitaire Ziekenhuizen KU Leuven
Lead Sponsor
P
Pulderbos revalidatiecentrum
Collaborating Sponsor
AI-Summary
What this Trial Is About
A mixed longitudinal design study will be carried out to explore the onset and time course of morphological muscle changes on a macroscopic level in children with spastic cerebral palsy (SCP). Therefore, this project aims to (1) describe the macroscopic morphological muscle changes with increasing age and (2) evaluate the onset and development of muscle alterations in relation to the brain lesion (e.g., timing, extent and location), to the neuromuscular impairments and to treatment. Overall, this project will evaluate the macroscopic muscle properties by means of 3D freehand ultrasound (3DfUS).
CONDITIONS
Official Title
Evaluation of Macroscopic Muscle Growth in Infants and Young Children With Spastic Cerebral Palsy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Confirmed diagnosis of spastic cerebral palsy or patients at high-risk for spastic cerebral palsy
- Suspected GMFCS levels I-III (Gross Motor Function Classification Scale expressing overall functional impairment level)
You will not qualify if you...
- Non-ambulatory status
- Botulinum neurotoxin type-A injections within 6 months prior to enrollment
- Lower limb surgery within 2 years prior to enrollment
- Muscle surgery at the muscles in the lower limb
- History of selective dorsal rhizotomy treatment
- Presence of ataxia or dystonia
- Severe co-morbidities such as severe epilepsy or severe behavior problems that interfere with cooperation
AI-Screening
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Trial Site Locations
Total: 1 location
1
UZ Leuven
Leuven, Vlaams-Brabant, Belgium, 3000
Actively Recruiting
Research Team
N
Nathalie De Beukelaer
CONTACT
L
Lauraine Staut
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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