Actively Recruiting
Evaluation of MicroRNAs and Vitamin B12 Expression in Subjects with Neurologic Symptoms of Depression, Anxiety and Fatigue in Long COVID-19
Led by Instituto Nacional de Rehabilitacion · Updated on 2025-03-07
20
Participants Needed
1
Research Sites
19 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
At the moment, the number of people with long COVID is unkown because there is still no effective diagnosis. This is why is very important to analyze the most common symptoms, which are: depression, anxiety and fatigue. This project seeks to analyze some blood components of people with long COVID, such as microRNAs and vitamin B12, in order to identify the body processes that changed after COVID-19 and thereby design better therapies and diagnostic methods focused on each of them. The hypothesis is that the expression of miR-21, -146a and -155 will be overexpressed as well as there will be a deficiency of vitamin B12 in serum in subjects suffering from long COVID with neurological symptoms of depression, anxiety and fatigue.
CONDITIONS
Official Title
Evaluation of MicroRNAs and Vitamin B12 Expression in Subjects with Neurologic Symptoms of Depression, Anxiety and Fatigue in Long COVID-19
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Subjects with confirmed diagnosis of COVID-19 by SARS-CoV-2 infection by PCR or antigen testing.
- Presence of neurological symptoms of depression, anxiety and fatigue associated with COVID-19 after three months from the first day of acute infection symptoms.
- Age between 18 and 65 years.
You will not qualify if you...
- Symptoms of acute infection in the last twelve weeks.
- Premorbid neurological alterations.
- Fewer than 2 doses of COVID-19 vaccine or last dose given less than 3 months ago.
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Instituto Nacional de Rehabilitación
Mexico City, Mexico City, Mexico, 14389
Actively Recruiting
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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