Actively Recruiting
Evaluation of the Safety of Terahertz Scanning System on Corneas
Led by Singapore Eye Research Institute · Updated on 2025-05-16
5
Participants Needed
1
Research Sites
108 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This observational study aims to establish the safety profile of the use of Terahertz (THz) scanning system on corneal diseases. Participants with "non-seeing" eyes but normal corneas will undergo THz scanning. Eye examinations will be conducted at baseline, immediately after scanning, and at 1 day, 1 week, and 1 month post-scanning. These examinations will include measurements of visual acuity, eye structural, retinal health, corneal cell morphology, and corneal nerve status. The investigators hypothesize that the THz scanning system is safe for application to the human cornea.
CONDITIONS
Official Title
Evaluation of the Safety of Terahertz Scanning System on Corneas
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Be at least 21 years of age
- Any gender (male or female)
- Any race (Chinese, Malay, Indian, Eurasian, others)
- Willing and able to follow all study instructions and attend scheduled visits
- Have at least one eye that is functionally blind but has a healthy cornea
- Able to keep face sufficiently stable for necessary scans
- Best spectacle corrected visual acuity (BSCVA) in the study eye of hand motion or worse
You will not qualify if you...
- Pregnant or breastfeeding women
- Eyes with previous major corneal surgery such as corneal transplantation, refractive surgery, or corneal cross-linking
- Eyes with previous infectious keratitis
- Eyes with long-term use of glaucoma eye drops
- Eyes with known moderate or severe meibomian gland dysfunction
- Eyes with active inflammation, infection, or chronic ocular surface inflammation
- Systemic diseases affecting the ocular surface, such as systemic autoimmune diseases
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Singapore National Eye Centre
Singapore, Singapore, Singapore, S169856
Actively Recruiting
Research Team
Y
Yu-Chi Liu
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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