Actively Recruiting
Validation of the Use of Terahertz Scanning System on Corneal Scars and Corneal Edema
Led by Singapore Eye Research Institute · Updated on 2025-05-21
150
Participants Needed
1
Research Sites
113 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This observational study aims to validate the use of THz scanning system in corneal edema and corneal scars, and to investigate the accuracy and performance on the use of THz scanning system in the evaluation of the progression of corneal edema and corneal scars. Participants corneal scars and corneal edema will undergo THz scanning, followed by a series of conventional clinical examinations for detailed characterization of the corneal lesion. The performance of the use of THz system on corneal scars and edema will be evaluated by correlating measurements from the THz scans with those obtained from standard clinical methods. The investigators hypothesize that the THz scanning system has the capacity to evaluate the hydration level on human corneas.
CONDITIONS
Official Title
Validation of the Use of Terahertz Scanning System on Corneal Scars and Corneal Edema
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Be at least 21 years of age
- Any gender (male or female)
- Any race (Chinese, Malay, Indian, Eurasian, or others)
- Willing and able to follow study instructions and schedule
- Patients with corneal endothelial dysfunction (Fuchs' dystrophy or bullous keratopathy) at any stage or patients with corneal scars without corneal edema
- Ability to keep face stable for scans
You will not qualify if you...
- Eyes with active inflammation or infection or chronic ocular surface inflammation
- Unable to give consent
- Physically immobile or poor compliance with instructions
- Determined by the principal investigator
- Pregnant or breastfeeding women
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Singapore National Eye Centre
Singapore, Singapore, S169856
Actively Recruiting
Research Team
Y
Yu-Chi Liu, MD, MCI, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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