Actively Recruiting
Evaluation of Serum- and OCT Biomarkers in Patients With DME Treated With Anti-VEGF or Dexamethasone Implant
Led by Vastra Gotaland Region · Updated on 2025-11-21
150
Participants Needed
2
Research Sites
178 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study aims to investigate the association between serum biomarkers and clinical response to anti-VEGF or dexamethasone implant by assessing OCT-biomarkers in patients with diabetic macular edema, DME, and to compare these with a group of naive patients (those not previously treated for DME).
CONDITIONS
Official Title
Evaluation of Serum- and OCT Biomarkers in Patients With DME Treated With Anti-VEGF or Dexamethasone Implant
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of type I or type II diabetes mellitus
- Diabetic macular edema involving the center of the fovea with central foveal thickness over 280 microns and presence of intraretinal cysts
You will not qualify if you...
- Any prior history of other macular diseases
- Previous dexamethasone implant treatment within the last six months for patients in the anti-VEGF group
- Previous anti-VEGF treatment within the last two months for patients in the dexamethasone implant group
- Prior vitreoretinal surgery
- Previous laser treatment of the macula
- Previous panretinal photocoagulation
- Ocular surgery within the previous 3 months
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Sahlgrenska University Hospital, Department of Ophthalmology
Mölndal, Sweden, 431 80
Actively Recruiting
2
Ögonmottagning Mölndal/SU
Mölndal, Sweden, 43130
Not Yet Recruiting
Research Team
I
Imadeddin Abu Ishkheidem, M.D.
CONTACT
S
Sofia Töyrä Silfverswärd, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
3
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