Actively Recruiting

Age: 18Years +
FEMALE
Healthy Volunteers
NCT05507853

Exploring Central Sensitization in Pregnant Women

Led by Göteborg University · Updated on 2025-04-01

144

Participants Needed

1

Research Sites

124 weeks

Total Duration

On this page

Sponsors

G

Göteborg University

Lead Sponsor

V

Vastra Gotaland Region

Collaborating Sponsor

AI-Summary

What this Trial Is About

Pelvic Girdle Pain (PGP) is reported by 50% of pregnant women and up to 11 years after pregnancy, 10% of women have persistent and per definition chronic PGP. Central (nervous system) sensitization that elicits pain hypersensitivity, may be one explanation. The overall aim of this study is to explore features of central sensitization in pregnant women and its predictive ability on physical activity, functioning and health in women with PGP. Measurements of central sensitization will be done on two study groups, pregnant women with PGP and healthy controls. To identify women at risk to develop chronic pain in relation to a common pain experience ie PGP in pregnancy, may help us understand if central sensitization early in life explains why women develop chronic pain.

CONDITIONS

Official Title

Exploring Central Sensitization in Pregnant Women

Who Can Participate

Age: 18Years +
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Pregnant women (first pregnancy or previous experience of pregnancy)
  • At least 18 years old
  • Carrying a single fetus pregnancy
  • Between 20 and 30 weeks of gestation
  • Able to read and understand Swedish or English
Not Eligible

You will not qualify if you...

  • History of fracture or malignant disease in the back, pelvis, pelvic floor, or hips
  • Presence of systemic disease affecting the musculoskeletal or nervous system
  • Conditions such as gestational diabetes, type 1 or 2 diabetes, or hypertension
  • Obstetric complications
  • Any contraindications for study tests

AI-Screening

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Trial Site Locations

Total: 1 location

1

Närhälsan Gibraltargatan

Gothenburg, Sweden, 43654

Actively Recruiting

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Research Team

A

Annelie Gutke, associate professor

CONTACT

S

Sonia Coelho Cristovao, PhD-student

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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