Actively Recruiting

Age: 20Years - 45Years
All Genders
ID07314034

Facially Driven Digital Workflow for Esthetic and Functional Full-mouth Rehabilitation

Led by Menoufia University · Updated on 2026-01-02

10

Participants Needed

1

Research Sites

17 weeks

Total Duration

On this page

Sponsors

M

Menoufia University

Lead Sponsor

M

Mansoura University

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are evaluating a fully digital, facially guided approach to full-mouth rehabilitation for adults with bite difficulties, smile dissatisfaction, and missing mandibular molars. This study focuses on patients with malocclusion and partial or complete tooth loss who need esthetic and functional dental restoration. The goal is to assess how integrated digital planning combining intraoral, facial, and CBCT scans can improve the precision and outcomes of dental rehabilitation. The treatment uses advanced digital planning to create a 3D virtual patient model that guides esthetic design, occlusion, and implant placement. Participants receive conservative anterior rehabilitation with lithium disilicate veneers, zirconia crowns, guided implant placement for missing molars, and temporary anchorage device-assisted intrusion of extruded molars. This fully digital workflow aims for precise restoration positioning, functional occlusion, and esthetic results. During the study, participants will undergo scans, treatments, and follow-up visits as part of the digital workflow. Researchers will measure implant stability 12 months after treatment to evaluate the success of the rehabilitation. Participants are expected to comply with treatment and follow-up protocols, and will be monitored for functional and esthetic outcomes using integrated digital data throughout the study period.

CONDITIONS

Brief Title

"Facially Driven Digital Full-Mouth Rehabilitation"

Who Can Participate

Age: 20Years - 45Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 20-45 years with partial or complete edentulism requiring full-mouth rehabilitation.
  • Patients with bite dysfunction, malocclusion, or esthetic concerns suitable for digital workflow treatment.
  • Adequate bone volume for implant placement or candidates for TAD-assisted tooth movement.
  • Willingness to undergo treatment using a fully digital, facially guided workflow and comply with follow-up visits.
  • Ability to provide informed consent.
Not Eligible

You will not qualify if you...

  • Systemic conditions contraindicating implant or surgical procedures (e.g., uncontrolled diabetes, immunosuppression).
  • Active oral infections or untreated periodontal disease.
  • Heavy smokers (>10 cigarettes/day) or substance abuse.
  • History of head and neck radiation therapy or bisphosphonate use.
  • Pregnancy or breastfeeding.
  • Inability to comply with treatment or follow-up protocol.

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Implementation

Duration - Variable based on individual treatment plan

Participants undergo a fully digital, facially guided full-mouth rehabilitation that includes guided implant placement, temporary anchorage device-assisted molar intrusion, and placement of custom veneers and crowns to restore bite function and smile esthetics.

Multiple visits for scans, treatment procedures, and device placements

Long-term Monitoring

Duration - Up to 12 months post-treatment

Participants are monitored for implant stability and functional and esthetic outcomes following treatment.

Periodic follow-up visits over 12 months

Trial Site Locations

Total: 1 location

1

Faculty of Dentistry

Shibīn al Kawm, Menoufia, Egypt

Actively Recruiting

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Research Team

M

Mohammed A. El-Sawy, PhD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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