Study Comparing Clinician and VentilO App Settings for One-Lung Ventilation During Thoracic Surgery to Assess Respiratory Acidosis Frequency and Severity

What this Trial Is About

Researchers are studying patients undergoing thoracic surgery with one-lung ventilation, a type of mechanical ventilation used during these procedures. The study aims to evaluate whether the initial ventilation settings, specifically tidal volume and respiratory rate, are suitable to prevent respiratory acidosis, a condition where carbon dioxide builds up in the blood. The study also compares the ventilation settings chosen by clinicians with those suggested by a smartphone application called VentilO. Participants receive one-lung ventilation with volume-controlled ventilation mode during surgery. The study observes the arterial blood gases during this ventilation and collects data retrospectively. There is no intervention beyond observation, and the study focuses on comparing clinician decisions with app recommendations for ventilation parameters. Participants will have their respiratory status monitored, including acid-base balance and respiratory rate at the start of one-lung ventilation, and respiratory acidosis 20 minutes after ventilation starts. Additional outcomes include the occurrence of hemodynamic shock or hypotension on the day after surgery, hospital length of stay, mechanical ventilation duration, and hospital mortality up to 90 days. The study involves reviewing clinical data without additional procedures, spanning from surgery through up to 90 days of follow-up.

Frequency and Severity of Respiratory Acidosis During One-lung Ventilation, a Retrospective Pilot Study to Compare Clinician Settings and Those Proposed by the VentilO Application