Actively Recruiting

Age: 18Years +
All Genders
ID07191743

Assessment of Physical Function in Critically Ill Patients With the Chelsea Critical Care Assessment Tool (CPAX)

Led by Universidade Federal do Rio de Janeiro · Updated on 2025-09-25

186

Participants Needed

1

Research Sites

74 weeks

Total Duration

On this page

Sponsors

U

Universidade Federal do Rio de Janeiro

Lead Sponsor

H

Hospital Universitario Pedro Ernesto

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are conducting a prospective, longitudinal observational study to assess physical function in critically ill adult patients in the Intensive Care Unit (ICU). The study focuses on using the Chelsea Critical Care Physical Assessment Tool (CPAx) to monitor functional status and analyze how changes in CPAx scores might predict clinical outcomes like mortality and the length of mechanical ventilation. The study includes collecting demographic and clinical data such as age, sex, ICU admission cause, comorbidities, and clinical scores like SOFA, SAPS III, and Charlson Comorbidity Index. Adult patients admitted to the general ICU at Pedro Ernesto University Hospital (HUPE) are observed during their ICU stay. Physical function is assessed with the CPAx at ICU admission and discharge. Data on respiratory support methods, including invasive mechanical ventilation, non-invasive ventilation, and high-flow nasal cannula, as well as renal replacement therapy, extubation, and reintubation, will be recorded. The study also tracks ICU and hospital length of stay and days on mechanical ventilation. Participants will be evaluated through functional assessments at ICU admission and discharge, along with collection of clinical information during their ICU stay. Researchers will measure CPAx score changes and monitor outcomes such as hospital mortality over 12 months, mechanical ventilation days over 6 months, and ICU length of stay. Secondary measures include extubation and reintubation rates within 30 days. The study aims to better understand how physical function relates to recovery and adverse outcomes in critically ill patients.

CONDITIONS

Brief Title

Functional Assessment in Critically Ill Patients

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patients admitted to Pedro Ernesto University Hospital (HUPE) General ICU
  • Age 18 years or older
  • ICU stay of 48 hours or longer
Not Eligible

You will not qualify if you...

  • Pregnancy
  • Unable to record CPAx score within the first 48 hours of ICU admission or on ICU discharge day
  • ICU readmission
  • Known neuromuscular or neurological diseases causing generalized weakness

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Monitoring

Duration - Duration of ICU stay (minimum 48 hours)

Participants admitted to the ICU have their physical function assessed using the Chelsea Critical Care Assessment Tool (CPAX) at ICU admission and discharge, along with clinical and demographic data collection during their ICU stay.

2 assessments (at ICU admission and ICU discharge)

Long-term Monitoring

Duration - Up to 12 months

Participants' clinical outcomes such as hospital mortality, mechanical ventilation duration, ICU length of stay, and hospital length of stay are observed up to 12 months following ICU admission.

Follow-up assessments according to hospital records; no additional visits required

Trial Site Locations

Total: 1 location

1

Pedro Ernesto University Hospital

Rio de Janeiro, Rio de Janeiro, Brazil, 20551-030

Actively Recruiting

Loading map...

Research Team

R

RAFAELA S PAIM

G

GABRIEL G MAIA, PhD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

Similar Trials

Feasibility and Safety of Early Mobilization and Rehabilitat...

Intensive Care Unit Acquired Weakness

Actively Recruiting

4 locations

Intensive Rehabilitation by Functional Electrical Stimulatio...

Intensive Care Unit (ICU) Acquired Weakness (ICU - AW)

Actively Recruiting

1 location

Frequently Asked Questions

Have more questions? Get in touch with our team for quick support

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here