Actively Recruiting

Age: 18Years - 100Years
All Genders
NCT03793062

Genetic and Epigenetic Basis of Chronic Wounds

Led by University of Pittsburgh · Updated on 2026-04-14

256

Participants Needed

1

Research Sites

525 weeks

Total Duration

On this page

Sponsors

U

University of Pittsburgh

Lead Sponsor

N

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Collaborating Sponsor

AI-Summary

What this Trial Is About

This pilot study is designed for chronic wounds that fail to heal in a timely manner carry specific genetic signatures. These genetic signatures will be studied using debrided wound tissue that is removed by the wound care provider as part of standard of care. The reference genomic signature will be evaluated by obtaining blood samples and will be compared with wound debrided tissue genomic signature to understand wound specific genomic changes.

CONDITIONS

Official Title

Genetic and Epigenetic Basis of Chronic Wounds

Who Can Participate

Age: 18Years - 100Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 63 18 years
  • Willing to comply with protocol instructions, including all study visits and study activities
  • Chronic wounds present for more than four weeks
  • Clinically diagnosed diabetic or non-diabetic ulcer
  • For patients with multiple wounds, the largest wound will be used for the study
Not Eligible

You will not qualify if you...

  • Unable to understand the procedures, risks, and benefits of the study or unable to provide informed consent
  • Pregnant females (self-declared) or lactating
  • Marked immunodeficiency (HIV/AIDS or use of immune-suppressive medications)
  • Prisoners

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

UPMC Wound Care Centers

Pittsburgh, Pennsylvania, United States, 15213

Actively Recruiting

Loading map...

Research Team

P

Piya Das Ghatak, PhD, MS

CONTACT

S

Sashwati Roy, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here