Actively Recruiting
Genetic Markers of Cardiovascular Disease in Epilepsy
Led by Mayo Clinic · Updated on 2025-09-08
600
Participants Needed
1
Research Sites
813 weeks
Total Duration
On this page
Sponsors
M
Mayo Clinic
Lead Sponsor
A
American Heart Association
Collaborating Sponsor
AI-Summary
What this Trial Is About
Epilepsy is a common condition which affects over 3 million people in the US. Patients with uncontrolled epilepsy have a lifetime risk of sudden unexpected death (SUDEP) of 35%, which is greatest in those under 40 years of age. The exact mechanisms and causes are not understood but can be due to underlying conditions which affect the heart and brain, which may lead to dangerous heart rhythms and death. Some of these conditions which affect heart and brain have an identifiable genetic cause. This study aims to identify known genetic causes of heart rhythm and sudden death related disorders in patients with epilepsy.
CONDITIONS
Official Title
Genetic Markers of Cardiovascular Disease in Epilepsy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults ages 18 to 50 with epilepsy, seizures, syncope, drowning, cardiac arrest, sudden death, or abnormal ECG suggesting arrhythmia
- Blood relatives aged 18 or older of patients with history of epilepsy, seizures, cardiac arrest, sudden death, drowning, syncope, or arrhythmia
You will not qualify if you...
- Unable to provide written consent
- Prisoners
- Seizures caused by ischemic events
- Seizures caused by traumatic brain injury
- History of cranial surgery
- History of brain tumor
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Mayo Clinic
Rochester, Minnesota, United States, 55905
Actively Recruiting
Research Team
S
Somers CPL Lab
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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