Actively Recruiting

Phase 3
Age: 18Years +
All Genders
Healthy Volunteers
NCT05006482

Geriatric Evaluation and Management With Survivorship Health Education for Older Survivors of Cancer, GEM-S Trial

Led by University of Rochester · Updated on 2026-01-13

668

Participants Needed

45

Research Sites

234 weeks

Total Duration

On this page

Sponsors

U

University of Rochester

Lead Sponsor

N

National Cancer Institute (NCI)

Collaborating Sponsor

AI-Summary

What this Trial Is About

This phase III trial compares the effect of geriatric evaluation and management with survivorship health education (GEM-S) to usual care on patient-reported physical function in older survivors of cancer. Survivorship care for older adults of cancer usually consists of getting advice from their doctor. This advice may include how to do their daily activities, so they are less tired or how to manage multiple diseases, or long-term side effects from treatment. GEM-S may help improve the physical ability to perform activities of daily living, mental well-being, and memory in older survivors of cancer after chemotherapy. This study may help doctors learn if including GEM-S in their practices improves physical, mental and memory functions in their patients. The study may also help to understand how such care affects cancer patients and their caregivers' quality of life.

CONDITIONS

Official Title

Geriatric Evaluation and Management With Survivorship Health Education for Older Survivors of Cancer, GEM-S Trial

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Participating clinical practices must identify at least one licensed oncologist or advanced practice practitioner willing to participate
  • Oncologists/APPs must have no plans to leave or retire from the practice within one year of enrollment
  • Practices must have support from oncology clinicians to participate in training and study procedures
  • Cancer survivors must be 65 years or older
  • Cancer survivors must have completed or will complete curative-intent treatment for solid tumor or lymphoma within the last 6 months
  • Survivors receiving other treatments such as hormonal therapy, monoclonal antibodies, immunotherapy, or radiation are eligible
  • Survivors must be willing and able to attend study visits or consent and assessments remotely
  • Survivors must be willing and able to provide informed consent in person or remotely
  • Survivors must speak and understand English and/or Spanish, with Spanish-speaking enrollment subject to resource availability and approval
  • Caregivers must be 18 years or older
  • Caregivers are selected by the survivor as someone helpful in health matters and need not live with the survivor
  • Caregivers must speak and understand English and/or Spanish, with Spanish-speaking enrollment subject to resource availability and approval
Not Eligible

You will not qualify if you...

  • Cancer survivors with conditions preventing informed consent or participation (e.g., dementia) are excluded
  • Caregivers unable to understand the consent form or study procedures due to cognitive, health, or sensory impairments are excluded
  • Capacity to consent and participate will be determined by study coordinators and oncologists

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 45 locations

1

Lewis and Faye Manderson Cancer Center

Tuscaloosa, Alabama, United States, 35401

Actively Recruiting

2

Kaiser Permanente-Fremont

Fremont, California, United States, 94538

Actively Recruiting

3

Kaiser Permanente-San Francisco

San Francisco, California, United States, 94115

Actively Recruiting

4

Helen F Graham Cancer Center

Newark, Delaware, United States, 19713

Actively Recruiting

5

Medical Oncology Hematology Consultants PA

Newark, Delaware, United States, 19713

Actively Recruiting

6

Hawaii Cancer Care Inc - Waterfront Plaza

Honolulu, Hawaii, United States, 96813

Actively Recruiting

7

Straub Clinic and Hospital

Honolulu, Hawaii, United States, 96813

Actively Recruiting

8

Kapiolani Medical Center for Women and Children

Honolulu, Hawaii, United States, 96826

Actively Recruiting

9

Tripler Army Medical Center

Honolulu, Hawaii, United States, 96859

Actively Recruiting

10

Hawaii Cancer Care - Westridge

‘Aiea, Hawaii, United States, 96701

Actively Recruiting

11

Pali Momi Medical Center

‘Aiea, Hawaii, United States, 96701

Actively Recruiting

12

OSF Saint Anthony's Health Center

Alton, Illinois, United States, 62002

Actively Recruiting

13

Fairview Southdale Hospital

Edina, Minnesota, United States, 55435

Actively Recruiting

14

Hennepin County Medical Center

Minneapolis, Minnesota, United States, 55415

Actively Recruiting

15

Monticello Cancer Center

Monticello, Minnesota, United States, 55362

Actively Recruiting

16

Park Nicollet Clinic - Saint Louis Park

Saint Louis Park, Minnesota, United States, 55416

Actively Recruiting

17

Regions Hospital

Saint Paul, Minnesota, United States, 55101

Actively Recruiting

18

Lakeview Hospital

Stillwater, Minnesota, United States, 55082

Actively Recruiting

19

Rice Memorial Hospital

Willmar, Minnesota, United States, 56201

Actively Recruiting

20

Minnesota Oncology Hematology PA-Woodbury

Woodbury, Minnesota, United States, 55125

Actively Recruiting

21

Lake Regional Hospital

Osage Beach, Missouri, United States, 65065

Actively Recruiting

22

Noyes Memorial Hospital/Myers Cancer Center

Dansville, New York, United States, 14437

Actively Recruiting

23

Northwell Health/Center for Advanced Medicine

Lake Success, New York, United States, 11042

Actively Recruiting

24

Highland Hospital

Rochester, New York, United States, 14620

Actively Recruiting

25

Pluta Cancer Center

Rochester, New York, United States, 14623

Actively Recruiting

26

University of Rochester

Rochester, New York, United States, 14642

Actively Recruiting

27

Wilmot Cancer Institute at Webster

Webster, New York, United States, 14580

Actively Recruiting

28

Novant Health Breast Surgery - Greensboro

Greensboro, North Carolina, United States, 27403

Actively Recruiting

29

Novant Health Cancer Institute - Kernersville

Kernersville, North Carolina, United States, 27284

Actively Recruiting

30

Novant Health Cancer Institute - Mount Airy

Mount Airy, North Carolina, United States, 27030

Actively Recruiting

31

Novant Health Cancer Institute - Statesville

Stateville, North Carolina, United States, 28625

Actively Recruiting

32

Novant Health Cancer Institute - Thomasville

Thomasville, North Carolina, United States, 27360

Actively Recruiting

33

Novant Health Forsyth Medical Center

Winston-Salem, North Carolina, United States, 27103

Actively Recruiting

34

South Central Medical and Resource Center

Lindsay, Oklahoma, United States, 73052

Actively Recruiting

35

Geisinger Medical Center

Danville, Pennsylvania, United States, 17822

Actively Recruiting

36

Geisinger Cancer Center Dickson City

Dickson City, Pennsylvania, United States, 18519

Actively Recruiting

37

Community Medical Center

Scranton, Pennsylvania, United States, 18510

Actively Recruiting

38

Geisinger Wyoming Valley/Henry Cancer Center

Wilkes-Barre, Pennsylvania, United States, 18711

Actively Recruiting

39

Chesapeake Regional Medical Center

Chesapeake, Virginia, United States, 23320

Actively Recruiting

40

ThedaCare Regional Cancer Center

Appleton, Wisconsin, United States, 54911

Actively Recruiting

41

HSHS Sacred Heart Hospital

Eau Claire, Wisconsin, United States, 54701

Suspended

42

Saint Vincent Hospital Cancer Center Green Bay

Green Bay, Wisconsin, United States, 54301

Actively Recruiting

43

Saint Vincent Hospital Cancer Center at Saint Mary's

Green Bay, Wisconsin, United States, 54303

Actively Recruiting

44

Marshfield Medical Center-River Region at Stevens Point

Stevens Point, Wisconsin, United States, 54482

Actively Recruiting

45

Marshfield Medical Center - Weston

Weston, Wisconsin, United States, 54476

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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