Actively Recruiting

Age: 18Years +
All Genders
NCT05534009

Health Care Workers Cohort Study in the EuCARE Project (EuCARE-HCW)

Led by Euresist Network GEIE · Updated on 2025-09-19

1800

Participants Needed

7

Research Sites

193 weeks

Total Duration

On this page

Sponsors

E

Euresist Network GEIE

Lead Sponsor

C

Centro Hospitalar Lisboa Ocidental

Collaborating Sponsor

AI-Summary

What this Trial Is About

The WP3 healthcare workers cohort in EuCARE is an observational multicentre study including collection of retrospective (historical) and prospective data and sample collection from health care workers with either a vaccination or a confirmed SARS-CoV-2 infection. Samples from HCW are sent to central laboratories for WP2 study were the impact of different variants in humoral and cellular immunity is to be analysed by biostatistical methods and with artificial intelligence in WP5. This analysis will focus on the impact on vaccine escape of viral variants / viral sequences as well as on any escape from any combination of natural and vaccine induced immunity. Eight countries will participate (Portugal, Italy, Germany, Lithuania, Georgia, Russia, Vietnam and Mexico).

CONDITIONS

Official Title

Health Care Workers Cohort Study in the EuCARE Project (EuCARE-HCW)

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults over 18 years old who are healthcare workers
  • Must have documented information about their COVID-19 vaccination and infection status
  • For those previously infected, diagnosis must be confirmed by detection of SARS-CoV-2 RNA
  • Signed informed consent if required by ethical approval
Not Eligible

You will not qualify if you...

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AI-Screening

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Trial Site Locations

Total: 7 locations

1

Heinrich Heine university

Düsseldorf, Germany

Actively Recruiting

2

Azienda Socio-Sanitaria Territoriale Santi Paolo e Carlo

Milan, Italy

Actively Recruiting

3

Ieo Istituto Europeo Di Oncologia

Milan, Italy

Actively Recruiting

4

Viesoji Istaiga Vilniaus Uiversiteto Ligoninė Santaros klinikos

Vilnius, Lithuania

Actively Recruiting

5

Hospital Juan Ghaham Casasus

Villahermosa, Mexico

Actively Recruiting

6

Centro Hospitalar de Lisboa Ocidental

Lisbon, Portugal

Actively Recruiting

7

Bach Mai Hospital

Hanoi, Vietnam

Actively Recruiting

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Research Team

F

FRANCESCA INCARDONA, DR

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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