Actively Recruiting

Age: 18Years +
All Genders
ID07404774

Prospective Evaluation of Hemorrhoid Suture Mucopexy Combined With Laser Hemorrhoidoplasty for Symptomatic Hemorrhoidal Disease

Led by National and Kapodistrian University of Athens · Updated on 2026-02-11

100

Participants Needed

1

Research Sites

52 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to evaluate the combined use of suture mucopexy, a stitch-based lift of prolapsed tissue, with Laser Hemorrhoidoplasty (LHP) in adults who have moderate-to-severe hemorrhoids (Grades II-IV). The study focuses on how long patients need pain medication after the procedure and whether they achieve complete symptom relief. Secondary goals include assessing quality of life, safety issues like bleeding or urinary retention, and rates of hemorrhoid recurrence or the need for re-operation. Participants will all receive the same combined procedure, which does not use Doppler guidance. The suture mucopexy lifts the prolapsed tissue and ties off blood vessels, while the laser treatment shrinks and scars the hemorrhoidal cushions. This minimally invasive approach is being observed without a comparison group. Follow-up visits are scheduled for 6 weeks, 6 months, and 12 months after surgery. Throughout the study, patients will be monitored for pain relief duration and symptom improvement soon after the procedure. Researchers will also evaluate hemorrhoid severity scores, complications, and any reoperations over the year following treatment. The total participation includes these follow-up visits and safety assessments to understand the procedure's effects over time.

CONDITIONS

Brief Title

Hemorrhoid Suture Mucopexy Combined With Laser Hemorrhoidoplasty

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults (over 18 years old).
  • Symptomatic hemorrhoidal disease classified as Goligher Grades II, III, or IV.
  • Patients with or without recurrent hemorrhoids after prior treatments such as rubber band ligation, infrared coagulation, or Milligan-Morgan surgery.
Not Eligible

You will not qualify if you...

  • Acutely thrombosed hemorrhoids.
  • Presence of anal fistula or abscess requiring separate surgical management.
  • Active inflammatory bowel disease (Crohn's disease or Ulcerative Colitis) involving the rectum.
  • Previous stapled hemorrhoid surgery (Stapled Haemorrhoidopexy).

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Implementation

Duration - 1 day

Participants undergo a minimally invasive procedure combining laser ablation and suture mucopexy to treat symptomatic hemorrhoidal disease.

1 procedure visit (in-person)

Post-operative Follow-up

Duration - 12 months

Participants attend follow-up visits to monitor recovery, assess symptoms, and check for complications after the procedure.

3 visits at postoperative week 6, month 6, and month 12 (in-person)

Trial Site Locations

Total: 1 location

1

Ippokrateio Hospital

Athens, Greece

Actively Recruiting

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Research Team

G

George Theodoropoulos

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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