Actively Recruiting

Age: 18Years +
All Genders
ID06914336

Hepatic Doppler to Assess Venous Congestion During Invasive Mechanical Ventilation

Led by University Hospital, Brest · Updated on 2025-04-06

100

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are studying venous congestion in patients who are in the intensive care unit (ICU) and require invasive mechanical ventilation. The study aims to investigate how the systolic to diastolic hepatic vein velocity ratio (S/D) measured by hepatic vein Doppler relates to various indicators of venous congestion. The goal is to find a significant connection between this ratio and congestion markers. This observational study involves measuring the S/D ratio using hepatic vein Doppler ultrasound at specific times: 24 hours after intubation and then every 48 hours until the patient is extubated, for up to 12 weeks. The study does not involve any treatments or interventions but focuses on monitoring and assessing this ultrasound measurement over time. Participants will be assessed through repeated Doppler ultrasound scans and monitoring while on mechanical ventilation. Researchers will collect data on the S/D hepatic vein velocity ratio and relate it to clinical congestion indicators. The study will continue until extubation or for up to 12 weeks, with safety and health closely observed during this period. The main outcome measured is the S/D ratio at scheduled times after intubation.

CONDITIONS

Brief Title

Hepatic Doppler to Assess Venous Congestion During Invasive Mechanical Ventilation (DOHECOV)

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Intubated for more than 24 hours
  • Age 18 years or older
Not Eligible

You will not qualify if you...

  • Chronic end-stage renal disease on admission
  • Atrial fibrillation
  • Cirrhosis
  • Portal thrombosis
  • Refusal to participate
  • Non-opposition could not be obtained from themselves or their trusted support person in the event of incapacity
  • Under legal protection

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Monitoring

Duration - Up to 12 weeks

Participants are monitored with hepatic Doppler assessments during invasive mechanical ventilation to evaluate venous congestion.

Assessments every 48 hours after initial 24 hours post-intubation

Trial Site Locations

Total: 1 location

1

Chu Brest

Brest, France, 29200

Actively Recruiting

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Research Team

G

Gwenael PRAT, phD

H

Hamza CHRAIBI, phD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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