Actively Recruiting
Hepatic Doppler to Assess Venous Congestion During Invasive Mechanical Ventilation
Led by University Hospital, Brest · Updated on 2025-04-06
100
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying venous congestion in patients who are in the intensive care unit (ICU) and require invasive mechanical ventilation. The study aims to investigate how the systolic to diastolic hepatic vein velocity ratio (S/D) measured by hepatic vein Doppler relates to various indicators of venous congestion. The goal is to find a significant connection between this ratio and congestion markers. This observational study involves measuring the S/D ratio using hepatic vein Doppler ultrasound at specific times: 24 hours after intubation and then every 48 hours until the patient is extubated, for up to 12 weeks. The study does not involve any treatments or interventions but focuses on monitoring and assessing this ultrasound measurement over time. Participants will be assessed through repeated Doppler ultrasound scans and monitoring while on mechanical ventilation. Researchers will collect data on the S/D hepatic vein velocity ratio and relate it to clinical congestion indicators. The study will continue until extubation or for up to 12 weeks, with safety and health closely observed during this period. The main outcome measured is the S/D ratio at scheduled times after intubation.
CONDITIONS
Brief Title
Hepatic Doppler to Assess Venous Congestion During Invasive Mechanical Ventilation (DOHECOV)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Intubated for more than 24 hours
- Age 18 years or older
You will not qualify if you...
- Chronic end-stage renal disease on admission
- Atrial fibrillation
- Cirrhosis
- Portal thrombosis
- Refusal to participate
- Non-opposition could not be obtained from themselves or their trusted support person in the event of incapacity
- Under legal protection
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 12 weeks
Participants are monitored with hepatic Doppler assessments during invasive mechanical ventilation to evaluate venous congestion.
Assessments every 48 hours after initial 24 hours post-intubation
Trial Site Locations
Total: 1 location
1
Chu Brest
Brest, France, 29200
Actively Recruiting
Research Team
G
Gwenael PRAT, phD
H
Hamza CHRAIBI, phD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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