Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
ID06870019

Effects of GPS Tracking on Patient Adherence to Hepatitis C Treatment Among People Experiencing Unsheltered Homelessness

Led by University of Southern California · Updated on 2025-08-29

124

Participants Needed

2

Research Sites

52 weeks

Total Duration

On this page

Sponsors

U

University of Southern California

Lead Sponsor

V

Ventura County Medical Center

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are evaluating whether using GPS tracking can improve medication adherence among patients diagnosed with Hepatitis C virus infection who are also experiencing unsheltered homelessness and receiving care through street medicine. This study compares standard medical care for Hepatitis C alone versus standard care combined with GPS tracking to help locate and follow up with patients. The study addresses challenges in traditional healthcare models for homeless populations and aims to explore patient perspectives on GPS tracking in treatment. Participants are randomly assigned to one of two groups: one receives the standard Hepatitis C treatment provided through street medicine, while the other receives the same standard treatment plus a GPS tracker device. The GPS device is intended to assist healthcare providers in locating patients for follow-up care during the 8 to 12 weeks of daily medication treatment. This multi-site randomized controlled study includes individual interviews to understand patient experiences in both groups. During the study, participants will be monitored for medication adherence over 8 to 12 weeks, with treatment length also recorded. Researchers will assess sustained virologic response up to about 24 weeks through the study completion. Participants will receive regular street medicine care, and their medication use will be tracked. The study ensures ethical use of GPS tracking and does not involve initial HCV screening, which occurs before enrollment. The total participation time varies with the treatment course and follow-up.

CONDITIONS

Brief Title

Hepatitis C Tracker Study

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed with Hepatitis C infection
  • Experiencing unsheltered homelessness at study initiation
  • Speaks English or Spanish
  • Receiving street medicine care
  • Meet the American Association for the Study of Liver Diseases (AASLD) criteria for simplified treatment of Hepatitis C
Not Eligible

You will not qualify if you...

  • Prior engagement in Hepatitis C treatment
  • Decompensated cirrhosis; HBsAg positive
  • Current pregnancy
  • Known or suspected hepatocellular carcinoma
  • Prior liver transplantation

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Outpatient Treatment

Duration - 8 to 12 weeks

Participants receive standard medical care for Hepatitis C, with some receiving a GPS tracker device to support treatment adherence.

Daily medication during treatment period with visits as part of street medicine care

Follow-up

Duration - Up to 24 weeks

Participants are monitored after treatment to assess sustained virologic response and overall health outcomes.

Periodic follow-up visits through study completion

Trial Site Locations

Total: 2 locations

1

USC Street Medicine

Alhambra, California, United States, 91803

Actively Recruiting

2

Ventura County Medical Center

Ventura, California, United States, 93003

Actively Recruiting

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Research Team

A

Alexis Coulourides Kogan, PhD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

HEALTH_SERVICES_RESEARCH

Number of Arms

2

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