Actively Recruiting
Hereditary Pheochromocytoma Assessment of Tumour Immunologies
Led by Radboud University Medical Center · Updated on 2024-11-21
200
Participants Needed
1
Research Sites
260 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
In this study, the investigators are examining the role of the immune system in pheochromocytoma and paraganglioma. The investigators aim to examine the differences in the immune system between people who have these tumors with and without a hereditary predisposition. The investigators also want to see how the immune system changes during the development of the tumor in people with a hereditary predisposition. Finally, the investigators will compare the data with a control group of people without these tumors. Ultimately, the investigators hope that the results will contribute to the discovery of new immune system-targeted medications for pheochromocytoma and paraganglioma.
CONDITIONS
Official Title
Hereditary Pheochromocytoma Assessment of Tumour Immunologies
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Newly diagnosed patients with pheochromocytoma or paraganglioma (PPGL) or newly diagnosed patients with metastatic PPGL recurrence
- Patients with mutations predisposing to PPGL
- Confirmed PPGL by pathology (for tissue sample study)
- Aged over 18 years
You will not qualify if you...
- Unable to provide informed consent
- Active inflammatory or infectious diseases
- Other malignancies under active treatment (except basal cell carcinoma and in situ carcinomas)
- Using medications that affect the immune system
- Pregnancy or breastfeeding
- Self-reported alcohol consumption of more than 21 units per week
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Radboudumc
Nijmegen, Gelderland, Netherlands, 6525 GA
Actively Recruiting
Research Team
K
Kai Xu, M.D.
CONTACT
M
Marieke de Laat, M.D. PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
4
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