Actively Recruiting

Phase 1
Age: 50Years +
All Genders
NCT06513819

HIV and Alcohol Research Center Focused on Polypharmacy (HARP) Pilot 2 (2nd HARP Pilot Intervention)

Led by Yale University · Updated on 2026-01-15

100

Participants Needed

1

Research Sites

71 weeks

Total Duration

On this page

Sponsors

Y

Yale University

Lead Sponsor

N

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The focus of this pilot will be on falls and neurocognitive symptoms, and the impact of alcohol, cannabis use, and medications on these outcomes. The rationale is that alcohol use at any level may interact with neurocognitively active medications, alcohol, and cannabis use leading to falls and impaired cognition.

CONDITIONS

Official Title

HIV and Alcohol Research Center Focused on Polypharmacy (HARP) Pilot 2 (2nd HARP Pilot Intervention)

Who Can Participate

Age: 50Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Have HIV infection
  • Visited a local VA site within the past year
  • Current alcohol use indicated by AUDIT-C screening
  • Taking five or more non-ART medications including at least one neurocognitively active medication (such as benzodiazepines, opioids, muscle relaxants, sleeping medications, or selective serotonin reuptake inhibitors)
Not Eligible

You will not qualify if you...

  • Currently inpatient in a hospital
  • Diagnosed with Alcohol Use Disorder in the past 12 months
  • Test positive for moderate or severe Alcohol Use Disorder on the Alcohol Symptom Checklist during screening

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

VA Connecticut Healthcare System

West Haven, Connecticut, United States, 06516

Actively Recruiting

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Research Team

A

Amy C Justice, MD, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

PREVENTION

Number of Arms

1

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