Study of Hormonal Treatment for Heavy Menstrual Bleeding in Girls and Young Women Under 26 Comparing Those With and Without Bleeding Disorders

What this Trial Is About

This research aims to evaluate how well hormonal medications such as contraceptive pills, patches, injectable progestins, and hormonal intra-uterine devices manage heavy menstrual bleeding in adolescents and young adults with and without bleeding disorders. The study also looks at quality of life, hemoglobin, and iron levels in these groups. It is a prospective observational cohort study conducted by University Hospital, Geneva. Participants are adolescents and young adults under 26 years old who experience heavy menstrual bleeding and agree to start hormonal medication to reduce menstrual flow. The study compares those with bleeding disorders to those without over a follow-up period of 1 year. Hormonal medication is initiated at the start, and participants are observed throughout this time. During the study, participants complete questionnaires and have blood tests at baseline, 3, 6, and 12 months to track menstrual blood loss reduction, quality of life, hemoglobin, ferritin, and thrombin generation markers. Researchers monitor the percentage reduction in menstrual bleeding at 3, 6, and 12 months after starting medication. This detailed follow-up helps understand treatment impact on health and wellbeing over time.

Hormonal Management of Heavy Menstrual Bleeding in Adolescents