Actively Recruiting
Hormonal Management of Heavy Menstrual Bleeding in Adolescents and Young Adults With and Without a Bleeding Disorder: Prospective Observational Cohort Study
Led by University Hospital, Geneva · Updated on 2026-05-12
163
Participants Needed
1
Research Sites
21 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to evaluate how well hormonal medications such as contraceptive pills, patches, injectable progestins, and hormonal intra-uterine devices manage heavy menstrual bleeding in adolescents and young adults with and without bleeding disorders. The study also looks at quality of life, hemoglobin, and iron levels in these groups. It is a prospective observational cohort study conducted by University Hospital, Geneva. Participants are adolescents and young adults under 26 years old who experience heavy menstrual bleeding and agree to start hormonal medication to reduce menstrual flow. The study compares those with bleeding disorders to those without over a follow-up period of 1 year. Hormonal medication is initiated at the start, and participants are observed throughout this time. During the study, participants complete questionnaires and have blood tests at baseline, 3, 6, and 12 months to track menstrual blood loss reduction, quality of life, hemoglobin, ferritin, and thrombin generation markers. Researchers monitor the percentage reduction in menstrual bleeding at 3, 6, and 12 months after starting medication. This detailed follow-up helps understand treatment impact on health and wellbeing over time.
CONDITIONS
Brief Title
Hormonal Management of Heavy Menstrual Bleeding in Adolescents
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adolescents and young adults aged under 26 years
- Presenting to the gynecology consultation at University Hospital, Geneva
- Diagnosed with heavy menstrual bleeding (PBAC > 100)
- Willing to start hormonal medication to manage heavy menstrual bleeding
You will not qualify if you...
- Pregnant or planning to become pregnant during the study period
- Already using hormonal medication for menstrual management or contraception
- Known anatomical uterine pathology
- Using anticoagulant or antiaggregant agents
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 12 months
Participants who start hormonal medication are observed to assess menstrual blood loss, quality of life, and blood markers over time.
Visits at baseline, 3 months, 6 months, and 12 months
Trial Site Locations
Total: 1 location
1
Geneva University Hospitals
Geneva, Switzerland, 1205
Actively Recruiting
Research Team
D
Dehlia Moussaoui, MD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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