Actively Recruiting

Age: 16Years - 65Years
All Genders
Healthy Volunteers
NCT05713734

Bleeding of Unknown Cause: a Swiss Case-control Study

Led by University Hospital, Geneva · Updated on 2026-04-29

400

Participants Needed

7

Research Sites

208 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this prospective cohort is to identified specific biological patterns in patients with a bleeding of unknown cause and to study the specific mechanisms of the bleeding disorder for each subset of patients.

CONDITIONS

Official Title

Bleeding of Unknown Cause: a Swiss Case-control Study

Who Can Participate

Age: 16Years - 65Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Men with an ISTH BAT score greater than 3, including at least two other positive bleeding items if surgical bleeding is counted
  • Women with an ISTH BAT score greater than 5, including at least two other positive bleeding items if surgical or postpartum bleeding is counted
  • Participants aged between 16 and 65 years
Not Eligible

You will not qualify if you...

  • Ongoing pregnancy
  • Use of antithrombotic or non-steroidal anti-inflammatory drugs within 10 days before blood collection
  • Use of antifibrinolytic agents or blood products within 14 days before blood collection
  • Active cancer diagnosed within the last five years or treated within the last two years
  • Active autoimmune disease
  • Active chronic inflammatory disease
  • Severe liver disease (cirrhosis greater than Child A)
  • Stage 3 renal insufficiency
  • Active or recent infection within the last 30 days
  • Hospitalization within the last 3 months
  • Surgery within the last 3 months
  • Trauma requiring medical intervention within the last 3 months

AI-Screening

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Trial Site Locations

Total: 7 locations

1

Ospedale Regionale di Bellinzona

Bellinzona, Switzerland

Actively Recruiting

2

Inselspital - Universitätsspital Bern

Bern, Switzerland

Actively Recruiting

3

University Hospital

Geneva, Switzerland

Actively Recruiting

4

Centre Hospitalier Universitaire Vaudois

Lausanne, Switzerland

Actively Recruiting

5

Gruppo Ospedaliero Moncucco

Lugano, Switzerland

Actively Recruiting

6

Kantonsspital St.Gallen

Sankt Gallen, Switzerland

Actively Recruiting

7

USZ - Universitätsspital Zürich

Zurich, Switzerland

Actively Recruiting

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Research Team

A

Alessandro Casini

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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