Study Using Tilt Table Test and 24-Hour ECG to Evaluate Heart Autonomic Nervous Function in Ages 12 to 85

What this Trial Is About

Autonomic nervous system diseases can disrupt the circulatory system and may lead to dangerous heart rhythm problems and sudden cardiac death. This research focuses on finding clear, practical diagnostic methods to evaluate the function of the autonomic nervous system, especially the hearts autonomic nerves. The study aims to support better evaluation through the use of the Head-Up Tilt Test HUTT. The study analyzed 169 patient samples who underwent the vertical tilt test and 24-hour Holter electrocardiogram ECG data collected between February 13, 2023, and October 31, 2023. Researchers compared several heart rate variability indicators with the Composite Autonomic Scoring Scale CASS to identify those most closely related to sympathetic and vagus nerve functions. They then defined score intervals and analyzed the sensitivity and specificity of these indicators. Participants performed both the vertical tilt test and 24-hour Holter ECG simultaneously while receiving treatment at the hospital. Researchers examined heart rate variability and autonomic scoring data to evaluate cardiac autonomic nervous function. The primary outcome is to find the indicators most correlated with sympathetic and vagus nerves by December 31, 2025. This observational study includes participants aged 12 to 85 years and allows healthy volunteers to join.

HUTT to Assess Cardiac Autonomic Nervous Function