Actively Recruiting

Phase Not Applicable
Age: 45Years - 65Years
FEMALE
ID07615790

The Effect of a Structured Combined Exercise Program on Heart Rate Variability and Menopausal Symptoms in Postmenopausal Women: A Randomized Controlled Trial

Led by Fenerbahce University · Updated on 2026-05-29

40

Participants Needed

1

Research Sites

8 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to evaluate whether a structured combined exercise program can improve heart health, menopausal symptoms, sleep quality, and quality of life in postmenopausal women aged 45 to 65 years. It focuses on measuring heart rate variability as an indicator of nervous system control over the heart, alongside assessing menopausal symptoms and overall quality of life. The study compares women who participate in the exercise program with those who continue their usual daily activities. Participants in the exercise group will undergo a supervised 12-week structured combined exercise program, exercising twice a week for 45 minutes each session. Each session includes warm-up, balance, strengthening, coordination, flexibility, and cool-down exercises tailored to individual functional capacity under physiotherapist supervision. The control group will maintain their usual daily activities without any structured exercise intervention during the study. After the study, control participants will be informed about the exercise program and offered the chance to join. Throughout the study, researchers will assess heart rate variability, menopausal symptoms, sleep quality, quality of life, depressive symptoms, and hot flash frequency and severity at baseline, immediately after the 12-week program, and again 8 weeks later. Hot flashes will be tracked daily during the intervention and follow-up periods. The study involves careful monitoring and statistical analysis of these outcomes to understand the exercise program's effects on postmenopausal women's health.

CONDITIONS

Brief Title

Structured Combined Exercise Program in Postmenopausal Women: Effects on Heart Rate Variability and Menopausal Symptoms

Who Can Participate

Age: 45Years - 65Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Women in the postmenopausal period
  • Aged between 45 and 65 years
  • Able to communicate and cooperate with the researchers
  • Not participating in another structured exercise program
  • Willing to participate voluntarily in the study
Not Eligible

You will not qualify if you...

  • Presence of severe cardiovascular, neurological, orthopedic, or psychiatric disease
  • Hormone replacement therapy use during the study period
  • Cognitive impairment affecting participation
  • Uncontrolled hypertension or other unstable medical conditions
  • Regular participation in structured exercise training within the last 6 months
  • Smoking or alcohol use that may affect heart rate variability measurements

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Outpatient Treatment

Duration - 12 weeks

Participants take part in a supervised 12-week structured combined exercise program performed twice weekly. Each 45-minute session includes warm-up, balance, strengthening, coordination, flexibility, and cool-down exercises tailored to individual functional capacity.

Twice-weekly supervised exercise sessions

Follow-up

Duration - 8 weeks

Participants are monitored for 8 weeks after completing the exercise program to assess heart rate variability, menopausal symptoms, sleep quality, quality of life, depressive symptoms, and hot flash frequency and severity.

Daily symptom tracking during follow-up period

Trial Site Locations

Total: 1 location

1

Fenerbahce University

Istanbul, Atasehir, Turkey (Türkiye)

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Research Team

B

Burcu Akkurt, PhD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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