Actively Recruiting

Phase Not Applicable
All Genders
NCT03065686

Identification of Genetic Factors Implicated in Orofacial Cleft Using Whole Exome Sequencing

Led by Centre Hospitalier Universitaire, Amiens · Updated on 2026-05-13

30

Participants Needed

1

Research Sites

573 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Despite significant progress made in identification on numerous genes and gene pathways critical for craniofacial development, several approaches, ie mutation screening of specific candidates, association studies and even genome-wide scans have largely failed to reveal the molecular basis of NS human clefting

CONDITIONS

Official Title

Identification of Genetic Factors Implicated in Orofacial Cleft Using Whole Exome Sequencing

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Subject with a NSCL/P or CL/P of unknown etiology
  • National health care insurance holders
Not Eligible

You will not qualify if you...

  • Subject with a CL/P of known etiology
  • Subject with a NSCL/P and an IRF6 mutation

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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2
3
+1

Trial Site Locations

Total: 1 location

1

CHU Amiens Picardie

Amiens, France, 80054

Actively Recruiting

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Research Team

B

Bénédicte DEMEER, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

BASIC_SCIENCE

Number of Arms

1

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