Actively Recruiting

Phase Not Applicable
Age: 5Years - 17Years
All Genders
NCT04763109

Identification of Pre-Malignant Lesions In Pediatric Patients With Neurofibromatosis Type 1 Using Novel Magnetic Resonance Imaging Techniques Paired With Artificial Intelligence

Led by Nicole Baca · Updated on 2026-05-07

15

Participants Needed

1

Research Sites

355 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a single arm pilot trial of a novel whole-body Magnetic Resonance Imaging paired with artificial intelligence intervention, to evaluate feasibility defined as scan-rescan reliability, and to estimate the positive predictive value of changes in Magnetic Resonance Imaging scans from baseline to 12-month visit using an Artificial Intelligence algorithm, among 15 pediatric patients with neurofibromatosis type 1 at Cedars-Sinai Medical Center.

CONDITIONS

Official Title

Identification of Pre-Malignant Lesions In Pediatric Patients With Neurofibromatosis Type 1 Using Novel Magnetic Resonance Imaging Techniques Paired With Artificial Intelligence

Who Can Participate

Age: 5Years - 17Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Between the ages of 5 and under 18 years at the start of the study; those who turn 18 during the study can enroll
  • Clinically or molecularly confirmed diagnosis of neurofibromatosis type 1 (NF-1), including mosaic or segmental NF-1
Not Eligible

You will not qualify if you...

  • Requires sedation for imaging
  • Has mechanical, magnetic, or electrical implants or devices
  • Has ferromagnetic implants or foreign bodies
  • Experiences claustrophobia or cannot lie facing upwards
  • Has allergy to animal dander or animal-instigated asthma

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Cedars Sinai Medical Center

Los Angeles, California, United States, 90048

Actively Recruiting

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Research Team

C

Clinical Trial Recruitment Navigator

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

OTHER

Number of Arms

1

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Identification of Pre-Malignant Lesions In Pediatric Patients With Neurofibromatosis Type 1 Using Novel Magnetic Resonance Imaging Techniques Paired With Artificial Intelligence | DecenTrialz